基于人群的因年龄和基础健康状况导致的重症 COVID-19 疾病高风险估计。

Population-based Estimates for High Risk of Severe COVID-19 Disease due to Age and Underlying Health Conditions.

作者信息

Laires Pedro A, Nunes Carla

机构信息

Centro de Investigação em Saúde Pública (CISP). Escola Nacional de Saúde Pública (ENSP). Universidade NOVA de Lisboa. Lisboa; Escola Nacional de Saúde Pública (ENSP). Universidade NOVA de Lisboa. Lisboa. Portugal.

Centro de Investigação em Saúde Pública (CISP). Escola Nacional de Saúde Pública (ENSP). Universidade NOVA de Lisboa. Lisboa. Escola Nacional de Saúde Pública (ENSP). Universidade NOVA de Lisboa. Lisboa. Portugal.

出版信息

Acta Med Port. 2020 Nov 2;33(11):720-725. doi: 10.20344/amp.14222. Epub 2020 Jul 24.

Abstract

INTRODUCTION

COVID-19 is a viral respiratory disease, which became a global threat to public health. Specific subsets of the population are more vulnerable, namely those with chronic diseases. We aimed to estimate the share of the Portuguese population at the highest risk for complications following COVID-19 infection due to both old age and specific comorbidities.

MATERIAL AND METHODS

Our sample included all people aged 65 years and above (2215 men and 3486 women) who participated in the fifth Portuguese National Health Interview Survey, conducted in 2014. In order to project the potential population at highest risk for COVID-19, we used the latest available official demographic estimates from the National Institute of Statistics - INE 2018. We used a more restrictive definition of risk combining old age criteria and the following chronic conditions as potential risk factors for COVID-19 according to the available literature: hypertension, diabetes, chronic obstructive pulmonary disease, cardio- and cerebrovascular disease.

RESULTS

We estimated that 15.5% (n = 1 560 667) of the Portuguese population might be at increased risk for complications from COVID-19 because of old age and existing chronic conditions. Such estimates vary across the country (from 1.7% in Azores to 33.7% in Northern Portugal). Northern Portugal not only has the highest prevalence of selected morbidity (72.8%) within mainland Portugal, but also has the largest population at risk for COVID-19 (n = 526 607). This was followed by the Lisbon and Tagus Valley region (n = 408 564) and Central Portugal (n = 388 867).

DISCUSSION

Our results should encourage authorities to continue protecting those more vulnerable to the pandemic threat, particularly on those areas of the country which are more likely to be further affected.

CONCLUSION

We projected a considerable number of Portuguese people at the highest risk for severe COVID-19 disease due to both old age and pre-existing chronic conditions. Such estimates vary across the country.

摘要

引言

新型冠状病毒肺炎(COVID-19)是一种病毒性呼吸道疾病,已成为对全球公共卫生的威胁。特定人群更容易感染,尤其是那些患有慢性病的人群。我们旨在估算因年老和特定合并症而在感染COVID-19后出现并发症风险最高的葡萄牙人口比例。

材料与方法

我们的样本包括2014年参与第五次葡萄牙全国健康访谈调查的所有65岁及以上人群(2215名男性和3486名女性)。为了预测COVID-19风险最高的潜在人群,我们使用了国家统计局(INE)2018年最新的官方人口估计数据。根据现有文献,我们采用了更严格的风险定义,将老年标准与以下慢性病作为COVID-19的潜在风险因素相结合:高血压、糖尿病、慢性阻塞性肺疾病、心脑血管疾病。

结果

我们估计,由于年老和现有慢性病,15.5%(n = 1 560 667)的葡萄牙人口可能因COVID-19而出现并发症的风险增加。这种估计在全国范围内有所不同(从亚速尔群岛的1.7%到葡萄牙北部的33.7%)。葡萄牙北部不仅在葡萄牙大陆选定发病率中患病率最高(72.8%),而且COVID-19风险人群数量也最多(n = 526 607)。其次是里斯本和塔霍河谷地区(n = 408 564)以及葡萄牙中部(n = 388 867)。

讨论

我们的结果应鼓励当局继续保护那些更容易受到大流行威胁的人群,特别是在该国更可能受到进一步影响的地区。

结论

我们预测,相当数量的葡萄牙人由于年老和先前存在的慢性病而面临患严重COVID-19疾病的最高风险。这种估计在全国范围内有所不同。

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