Division of Biology and Medicine, The Warren Alpert Medical School of Brown University, Brown University, Providence, Rhode Island, United States of America.
Department of Biology, The University of Puerto Rico, San Juan, Puerto Rico, United States of America.
PLoS One. 2022 Aug 11;17(8):e0272497. doi: 10.1371/journal.pone.0272497. eCollection 2022.
To study the relationship between county-level COVID-19 outcomes (incidence and mortality) and county-level median household income and status of Medicaid expansion of US counties.
Retrospective analysis of 3142 US counties was conducted to study the relationship between County-level median-household-income and COVID-19 incidence and mortality per 100,000 people in US counties, January-20th-2021 through December-6th-2021. County median-household-income was log-transformed and stratified by quartiles. Multilevel-mixed-effects-generalized-linear-modeling adjusted for county socio-demographic and comorbidities and tested for Medicaid-expansion-times-income-quartile interaction on COVID-19 outcomes.
There was no significant difference in COVID-19 incidence-rate across counties by income quartiles or by Medicaid expansion status. Conversely, for non-Medicaid-expansion states, counties in the lowest income quartile had a 41% increase in COVID-19 mortality-rate compared to counties in the highest income quartile. Mortality-rate was not related to income in counties from Medicaid-expansion states.
Median-household-income was not related to COVID-19 incidence-rate but negatively related to COVID-19 mortality-rate in US counties of states without Medicaid-expansion.
研究美国县 COVID-19 结果(发病率和死亡率)与县人均家庭收入以及医疗补助扩大状况之间的关系。
对 3142 个美国县进行回顾性分析,以研究 2021 年 1 月 20 日至 2021 年 12 月 6 日期间美国县人均家庭收入与每 10 万人 COVID-19 发病率和死亡率之间的关系。县人均家庭收入进行对数转换,并按四分位数分层。使用多级混合效应广义线性模型进行调整,以适应县社会人口统计学和合并症,并测试医疗补助扩展与收入四分位数的交互作用对 COVID-19 结果的影响。
按收入四分位数或医疗补助扩展状况划分,县 COVID-19 发病率没有显著差异。相反,在没有医疗补助扩展的州,收入最低四分位数的县 COVID-19 死亡率比收入最高四分位数的县高 41%。在医疗补助扩展州的县,死亡率与收入无关。
在没有医疗补助扩展的州,县人均家庭收入与 COVID-19 发病率无关,但与 COVID-19 死亡率呈负相关。