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基础皮质醇与反应性皮质醇与外化问题之间的关系:一项系统综述。

Relation between basal cortisol and reactivity cortisol with externalizing problems: A systematic review.

作者信息

Figueiredo Patrícia, Ramião Eduarda, Azeredo Andreia, Moreira Diana, Barroso Ricardo, Barbosa Fernando

机构信息

University of Porto, Portugal.

University of Porto, Portugal.

出版信息

Physiol Behav. 2020 Oct 15;225:113088. doi: 10.1016/j.physbeh.2020.113088. Epub 2020 Jul 21.

DOI:10.1016/j.physbeh.2020.113088
PMID:32707158
Abstract

Delinquent behavior describes one of the most severe forms of antisocial and aggressive behavior, causing the highest mental health and public expenditures of problematic behavior in adolescence. Literature suggests that different concentrations of cortisol may serve as a biological marker for a severe antisocial subgroup of adolescents, although from the environmental risk factors that play a role in the development of severe delinquent and aggressive behavior, other neurobiological factors may be important. This review aims to analyze the association of cortisol levels with the development of delinquent behavior. Studies related to the topic were obtained from multiple databases, through rigorous exclusion and inclusion criteria. Only papers with empirical and quantitative methodologies from scientific and academic publications were included. Aims, methodological aspects (sample and instruments), and main conclusions were extracted from each study. Overall, the data suggest that regardless of the literature relating low cortisol levels to conduct problems and antisocial behavior, the lack of consensus in the examined studies demonstrates that more studies are needed to reveal the role of biosocial mechanisms in this hormonal-behavior link, and how these mechanisms are involved in establishing and maintaining delinquent behavior.

摘要

犯罪行为描述了最严重的反社会和攻击性行为形式之一,在青少年中造成了心理健康问题和问题行为的最高公共支出。文献表明,不同浓度的皮质醇可能作为青少年严重反社会亚组的生物学标志物,尽管在严重犯罪和攻击性行为发展中起作用的环境风险因素方面,其他神经生物学因素可能也很重要。本综述旨在分析皮质醇水平与犯罪行为发展之间的关联。通过严格的排除和纳入标准,从多个数据库中获取了与该主题相关的研究。仅纳入了来自科学和学术出版物的具有实证和定量方法的论文。从每项研究中提取了目的、方法学方面(样本和工具)以及主要结论。总体而言,数据表明,尽管有文献将低皮质醇水平与行为问题和反社会行为联系起来,但在所审查的研究中缺乏共识表明,需要更多研究来揭示生物社会机制在这种激素 - 行为联系中的作用,以及这些机制如何参与建立和维持犯罪行为。

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