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一例局部晚期甲状旁腺癌经完整手术切除后实现三年无病生存的罕见病例。

A rare case of three years disease free survival in a locally advanced parathyroid carcinoma successfully excised by complete surgical resection.

作者信息

Sohail Abdul Ahad, Ayub Bushra, Abbas Syed Akbar, Sheikh Shafqat Ali, Qureshi Talha Ahmed, Usman Muhammad, Diwan Asad

机构信息

Department of Surgery, Aga Khan University Hospital, Pakistan.

Patel Hospital, Pakistan.

出版信息

Ann Med Surg (Lond). 2020 Jul 18;57:62-65. doi: 10.1016/j.amsu.2020.07.023. eCollection 2020 Sep.

Abstract

Parathyroid carcinoma (PC) is one of the rarest malignancies making approximately 0.005% of all cancers. It may arise sporadically or less commonly, in conjunction with genetic endocrine syndromes. Due to the rarity of the disease, no general consensus or definitive guidelines exist for its pre-operative diagnosis, management, or follow up. Surgical tumor removal is the gold standard treatment to prevent its recurrence. Parathyroid carcinoma has a high recurrence rate ranging from 40 to 60% in recent literature. We report a case of a seventy-year-old elderly female with locally advanced parathyroid carcinoma successfully surgically excised completely with a 3 year disease free survival period without adjuvant chemotherapy or radiotherapy.

摘要

甲状旁腺癌(PC)是最罕见的恶性肿瘤之一,约占所有癌症的0.005%。它可能散发出现,或较少见地与遗传性内分泌综合征相关。由于该疾病罕见,对于其术前诊断、管理或随访尚无普遍共识或明确指南。手术切除肿瘤是预防复发的金标准治疗方法。根据近期文献,甲状旁腺癌的复发率很高,在40%至60%之间。我们报告一例70岁老年女性局部晚期甲状旁腺癌患者,成功接受了完整的手术切除,无辅助化疗或放疗,疾病无进展生存期达3年。

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