Centro De Investigación E Innovación En Gerontología Aplicada (CIGAP), Facultad De Salud, Universidad Santo Tomás , Antofagasta, Chile.
Escuela De Psicología, Facultad De Ciencias Sociales Y De La Comunicación, Universidad Santo Tomás , Antofagasta, Chile.
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2021 Jul;28(4):543-558. doi: 10.1080/13825585.2020.1796915. Epub 2020 Jul 27.
Functional impairment (FI) relates to the condition of executive functions (EFs). While EFs become affected by age and educational level (EL). Seniors suffering from depression (SSDs) on the other hand show EF-related deficiencies; however, there is hardly any literature available regarding their relationship with FI in Latin SSDs, who usually have low ELs.
To verify the relationship between EFs and FI in SSDs of Latin origins, by controlling the effects associated with age and educational level.
Cross-sectional study, of cases and controls, conducted on a nonprobability sample, made up of 102 self-sufficient SSDs and 142 control subjects over age 50, monolinguals of Latin origin (Chileans), all assessed by means of a battery of assessments such as: Geriatric Depression Scale, Addenbrook's Cognitive Assessment III, Trail making Tests A and B, STROOP word-color test, and semantic and phonological verbal fluency tests. A domain of composite EFs was established with standardized Chilean population scores, where age and educational levels were controlled. A simple linear regression analysis was conducted to determine the relationship between EFs and FI in SSDs.
Upon controlling age and educational levels, EFs explained an FI variance of 3.9% in SSDs; depression explained an EF variance of 3.2%, and 3.7% of FI.
The results of the present study highlight the importance of a timely intervention when it comes to geriatric depression, considering the negative effect it has over the executive functions and the functionality of seniors.
功能障碍（FI）与执行功能（EF）的状况有关。而 EF 会受到年龄和教育程度（EL）的影响。另一方面，患有抑郁症的老年人（SSDs）表现出与 EF 相关的缺陷；然而，几乎没有关于拉丁裔 SSDs 中 EF 与 FI 之间关系的文献，这些患者通常 EL 较低。
通过控制与年龄和教育程度相关的影响，验证拉丁裔 SSDs 中 EF 与 FI 之间的关系。
这是一项病例对照的横断面研究，采用非概率抽样方法，由 102 名自理 SSDs 和 142 名年龄在 50 岁以上、母语为拉丁语（智利人）的对照组组成。所有参与者都接受了一系列评估，包括老年抑郁量表、Addenbrook 认知评估 III、连线测试 A 和 B、STROOP 字色测试以及语义和语音流畅性测试。建立了一个由标准化智利人群分数组成的综合 EF 域，其中控制了年龄和教育程度。进行了简单线性回归分析，以确定 SSDs 中 EF 和 FI 之间的关系。
在控制年龄和教育程度后，EF 解释了 SSDs 中 3.9%的 FI 方差；抑郁解释了 EF 方差的 3.2%和 FI 的 3.7%。
本研究结果强调了及时干预老年抑郁症的重要性，因为它对执行功能和老年人的功能有负面影响。
