Douedi Steven, Albayati Asseel, Alfraji Nasam, Mazahir Usman, Costanzo Eric
Department of Internal Medicine, Jersey Shore University Medical Center, Neptune, NJ, USA.
Department of Pulmonology and Critical Care, Jersey Shore University Medical Center, Neptune, NJ, USA.
Am J Case Rep. 2020 Jul 27;21:e925513. doi: 10.12659/AJCR.925513.
BACKGROUND Novel Coronavirus 2019 (COVID-19) has been defined as a pandemic infecting millions of individuals with a significantly high mortality and morbidity rate. Treatment and management for pregnant patients infected with COVID-19 has been poorly described in the literature. Furthermore, vertical transmission of COVID-19 to the fetus has been poorly described. The purpose of this case series is to present 3 patients in their trimester who underwent emergent cesarean sections and were successfully managed in the intensive care unit. CASE REPORT We present the cases of 3 patients diagnosed with COVID-19 via RT-PCR in their third trimester of pregnancy. All patients underwent emergent cesarean sections and were managed on mechanical ventilation in the intensive care unit and eventually discharged in stable condition. CONCLUSIONS Early cesarean section and aggressive management with mechanical ventilation has been shown to be very beneficial for mothers diagnosed with COVID-19 and their infants. All 3 patients were successfully extubated, and all 3 infants tested negative for COVID-19, suggesting no vertical transmission; although, further studies are needed to confirm this finding.
2019年新型冠状病毒(COVID-19)已被定义为一种大流行病,感染了数百万个体,死亡率和发病率极高。关于感染COVID-19的孕妇的治疗和管理,文献报道较少。此外,COVID-19垂直传播给胎儿的情况也鲜有描述。本病例系列的目的是介绍3例在孕晚期接受紧急剖宫产并在重症监护病房成功治疗的患者。病例报告:我们介绍了3例在妊娠晚期通过逆转录聚合酶链反应(RT-PCR)诊断为COVID-19的患者病例。所有患者均接受了紧急剖宫产,并在重症监护病房接受机械通气治疗,最终病情稳定出院。结论:早期剖宫产和积极的机械通气治疗已被证明对诊断为COVID-19的母亲及其婴儿非常有益。所有3例患者均成功拔管,所有3例婴儿的COVID-19检测均为阴性,提示无垂直传播;不过,需要进一步研究来证实这一发现。