Division of Gastroenterology/Hepatology, Department of Internal Medicine, University of Florida College of Medicine, 653 West 8th Street, Jacksonville, FL 32209, USA.
Division of Gastroenterology/Hepatology, Department of Internal Medicine, University of Florida College of Medicine, 653 West 8th Street, Jacksonville, FL 32209, USA.
Gastroenterol Clin North Am. 2020 Sep;49(3):607-621. doi: 10.1016/j.gtc.2020.05.001. Epub 2020 Jun 16.
Irritable bowel syndrome (IBS) is probably the most common diagnosis in gastroenterology involving the brain-gut axis. By definition, pain is the most frequent symptom experienced by patients. It is important to understand the biopsychosocial and physiologic aspects of the disease when discussing treatment of IBS. Such therapies as lifestyle modifications, changes in diet, and cognitive behavioral therapy should be used in conjunction with pharmacotherapy rather than pharmacotherapy alone. The pathophysiologic mechanisms are reviewed in this article along with the current treatments available, in the era of growing demand for more effective treatments for the pain component of IBS.
肠易激综合征（IBS）可能是涉及脑-肠轴的最常见的胃肠病学诊断。根据定义，疼痛是患者最常经历的症状。在讨论 IBS 的治疗时，了解疾病的生物心理社会和生理方面很重要。在药物治疗的同时，应使用生活方式改变、饮食改变和认知行为疗法等治疗方法。本文综述了病理生理机制以及目前可用的治疗方法，因为对 IBS 疼痛成分的更有效治疗的需求不断增长。
