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草药如何治疗特发性膜性肾病?

How Does Herbal Medicine Treat Idiopathic Membranous Nephropathy?

作者信息

Feng Zhendong, Liu Wenbin, Jiang Han Xue, Dai Haoran, Gao Chang, Dong Zhaocheng, Gao Yu, Liu Fei, Zhang Zihan, Zhao Qihan, Zhang Lei, Liu Baoli

机构信息

Department of Nephropathy, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.

Department of Nephropathy, Beijing Traditional Chinese Medicine Hospital Pinggu Hospital, Beijing, China.

出版信息

Front Pharmacol. 2020 Jul 3;11:994. doi: 10.3389/fphar.2020.00994. eCollection 2020.

DOI:10.3389/fphar.2020.00994
PMID:32719601
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7350518/
Abstract

Idiopathic membranous nephropathy (IMN) has made increasing progress in mechanism and treatment research. Herbal medicine is gradually being accepted as an alternative therapy in treating IMN. However, the intervention mechanism of herbal medicine in the treatment of membranous nephropathy is still unclear. In this review, we summarize some achievements of herb medicine in treating IMN and discuss the research direction of herb in IMN. Finally, we propose the dilemma about the study on the treatment of IMN with herb medicine. We hope that this article can bring some thoughts for clinical and scientific researchers on the treatment of IMN with herb medicine.

摘要

特发性膜性肾病(IMN)在发病机制和治疗研究方面取得了越来越多的进展。草药正逐渐被接受为治疗IMN的一种替代疗法。然而,草药治疗膜性肾病的干预机制仍不清楚。在这篇综述中,我们总结了草药治疗IMN的一些成果,并讨论了草药在IMN中的研究方向。最后,我们提出了草药治疗IMN研究中的困境。我们希望本文能为临床和科研人员在草药治疗IMN方面带来一些思考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8db/7350518/a547cbccdea1/fphar-11-00994-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8db/7350518/5d32f0a8495a/fphar-11-00994-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8db/7350518/1a19aa565bb4/fphar-11-00994-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8db/7350518/a547cbccdea1/fphar-11-00994-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8db/7350518/5d32f0a8495a/fphar-11-00994-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8db/7350518/1a19aa565bb4/fphar-11-00994-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8db/7350518/a547cbccdea1/fphar-11-00994-g003.jpg

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Int Urol Nephrol. 2024 Feb;56(2):699-706. doi: 10.1007/s11255-023-03682-2. Epub 2023 Jul 22.
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BMC Complement Med Ther. 2023 Apr 27;23(1):134. doi: 10.1186/s12906-023-03950-9.
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