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心理健康对于改善癫痫过渡期患者生活质量的重要性。

The importance of mental health in improving quality of life in transition-aged patients with epilepsy.

机构信息

The Children's Hospital of Eastern Ontario, Canada.

The Ottawa Hospital, Canada.

出版信息

Epilepsy Behav. 2020 Nov;112:107324. doi: 10.1016/j.yebeh.2020.107324. Epub 2020 Jul 25.

Abstract

OBJECTIVE

Adolescents with epilepsy are known to have a lower quality of life (QoL) than the typically developing adolescent population. In order to address this, treating physicians have primarily focused on obtaining seizure control. However, growing evidence suggests a strong relation between QoL and mental health in adults with epilepsy and other chronic conditions. Given the high rate of mental health issues in transition-aged adolescents with epilepsy, this study aimed to examine the relation between QoL and mental health.

METHODS

Baseline data from 107 transition-aged adolescents (M = 16.08 years; 52 males, 55 females) enrolled in an epilepsy transition clinic were analyzed for this study.

RESULTS

Analysis found that over 56% of participants showed some signs of mental illness, and that these participants had significantly lower QoL scores than those without mental health issues. Furthermore, regression analysis found that both depression and anxiety remained significant, independent predictors of QoL, even when significant epilepsy and demographic variables were accounted for (t(99) = -1.28, p < .001 and t(99) = -1.10, p = .002, respectively).

SIGNIFICANCE

Results suggest that in order to ensure best outcomes for these adolescents, it may be important for clinicians to take a holistic approach to treatment, managing and treating both seizures and mental health concerns.

摘要

目的

患有癫痫的青少年的生活质量(QoL)低于一般青少年群体。为了解决这个问题,治疗医生主要专注于获得癫痫发作控制。然而,越来越多的证据表明,癫痫和其他慢性病患者的 QoL 与心理健康之间存在密切关系。鉴于患有癫痫的青春期过渡青少年中精神健康问题的高发率,本研究旨在研究 QoL 与心理健康之间的关系。

方法

本研究分析了参加癫痫过渡诊所的 107 名青春期过渡青少年(M=16.08 岁;52 名男性,55 名女性)的基线数据。

结果

分析发现,超过 56%的参与者表现出一些精神疾病迹象,这些参与者的 QoL 评分明显低于没有心理健康问题的参与者。此外,回归分析发现,抑郁和焦虑仍然是 QoL 的显著、独立预测因素,即使考虑到重要的癫痫和人口统计学变量(t(99)=-1.28,p<.001 和 t(99)=-1.10,p=.002)。

意义

结果表明,为了确保这些青少年的最佳结果,临床医生可能需要采取整体治疗方法,同时管理和治疗癫痫发作和心理健康问题。

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