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阴茎癌患者动态前哨淋巴结活检(DSNB)的初步经验

[Initial Experiences of Dynamic Sentinel Lymph Node Biopsy (DSNB) in Patients with Penile Cancer].

作者信息

Abe Noriyuki, Hori Jun-Ichi, Kobayashi Shin, Kikuchi Daiki, Tateoka Joe, Watanabe Masaki, Wada Naoki, Tamaki Gaku, Kita Masafumi, Matsuya Taisuke, Ishida-Yamamoto Akemi, Kakizaki Hidehiro

机构信息

The Department of Urology, Kitasaito Hospital·The Department of Renal and Urologic Surgery, Asahikawa Medical University.

The Department of Renal and Urologic Surgery, Asahikawa Medical University.

出版信息

Hinyokika Kiyo. 2020 Jul;66(7):221-224. doi: 10.14989/ActaUrolJap_66_7_221.

DOI:10.14989/ActaUrolJap_66_7_221
PMID:32723976
Abstract

We present 2 cases of penile cancer in which the inguinal lymph node was not palpable and inguinal lymph node dissection (ILND) could be safely avoided by conducting dynamic sentinel lymph node biopsy (DSNB). The first case was in a 54-year-old man complaining of penile tumor for at least 3 months. We performed partial penectomy and DSNB. The pathological diagnosis was squamous cell carcinoma (SCC), pT2-3. There was no cancer metastasis in sentinel nodes (0/2). There has been no recurrence for 6 years after operation. The second case was 65-year-old man suffering from penile tumor for at least 6 months. We performed partial penectomy and DSNB. The pathological diagnosis was SCC,pT2. There was no cancer metastasis in sentinel nodes (0/3). There has been no recurrence for 1 year after operation. ILND has been recommended for intermediate and high-risk penile cancer even in patients with non-palpable inguinal lymph nodes. However,the complication of ILND is very high. DSNB has the potential to avoid ILND if there is no cancer metastasis in sentinel nodes.

摘要

我们报告2例阴茎癌患者,其腹股沟淋巴结不可触及,通过动态前哨淋巴结活检(DSNB)可安全避免腹股沟淋巴结清扫术(ILND)。第一例是一名54岁男性,主诉阴茎肿物至少3个月。我们实施了阴茎部分切除术和DSNB。病理诊断为鳞状细胞癌(SCC),pT2 - 3。前哨淋巴结无癌转移(0/2)。术后6年无复发。第二例是一名65岁男性,患有阴茎肿物至少6个月。我们实施了阴茎部分切除术和DSNB。病理诊断为SCC,pT2。前哨淋巴结无癌转移(0/3)。术后1年无复发。即使腹股沟淋巴结不可触及,对于中高危阴茎癌患者也推荐进行ILND。然而,ILND的并发症非常高。如果前哨淋巴结无癌转移,DSNB有可能避免ILND。

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