Venieri Danae, Gounaki Iosifina, Christidis George E, Knapp Charles W, Bouras-Vallianatos Petros, Photos-Jones Effie
School of Environmental Engineering, Technical University of Crete, 73100 Chania, Greece.
School of Mineral Resources Engineering, Technical University of Crete, 73100 Chania, Greece.
Minerals (Basel). 2020 Apr 14;10(4):348. doi: 10.3390/min10040348. eCollection 2020 Apr.
Medicinal earths are an important and yet, so far, little scientifically explored archaeological resource. They are almost always identified by their source locality. Our work over the last few years has focused on their chemical and mineralogical characterization and their testing as anti-bacterials. This paper presents the results of the mineralogical analysis and antibacterial testing of six medicinal earths, or (stamped earth) of unknown date and provenance in the Pharmacy Museum of the University of Basel. Only one of them, a red (Armenian?) 'bole', was found to be antibacterial against both Gram-positive and Gram-negative bacteria. A yellow powder of Terra Tripolitania was mildly antibacterial and against one pathogen only. We argue that medicinal earths are in a pivotal place to bridge the gap between currently dispersed pieces of information. This information relates to: (a) their nature, attributes, and applications as described in the texts of different periods, (b) the source of their clays and how best to locate them in the field today, and (c) the methods employed for their beneficiation, if known. We propose that work should be focused primarily onto those medicinal earths whose clay sources can be re-discovered, sampled and assessed. From then on, a parallel investigation should be initiated involving both earths and their natural clays (mineralogy at bulk and nano-sized levels, bio-geochemistry, microbiological testing). We argue that the combined study can shed light into the parameters driving antibacterial action in clays and assist in the elucidation of the mechanisms involved.
药用泥土是一种重要但迄今为止科学探索较少的考古资源。它们几乎总是根据其产地来识别。我们过去几年的工作重点是对它们进行化学和矿物学表征以及作为抗菌剂的测试。本文介绍了巴塞尔大学药博物馆中六种日期和来源不明的药用泥土或( stamped earth)的矿物学分析和抗菌测试结果。其中只有一种红色(亚美尼亚?)“陶土”对革兰氏阳性菌和革兰氏阴性菌均具有抗菌作用。的黎波里陶土黄色粉末具有轻微抗菌作用,且仅针对一种病原体。我们认为,药用泥土在弥合当前分散的信息碎片之间的差距方面处于关键地位。这些信息涉及:(a)不同时期文献中描述的它们的性质、属性和应用,(b)它们的粘土来源以及如今在野外如何最好地找到它们,以及(c)如果已知的话,用于它们选矿的方法。我们建议工作应主要集中在那些其粘土来源可以重新发现、采样和评估的药用泥土上。从那时起,应启动一项平行调查,涉及泥土及其天然粘土(宏观和纳米级矿物学、生物地球化学、微生物测试)。我们认为,综合研究可以阐明驱动粘土抗菌作用的参数,并有助于阐明其中涉及的机制。