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巨大典型肺类癌伴巨人症综合征。

Huge typical pulmonary carcinoid presented with gigantism syndrome.

机构信息

Department of General Thoracic Surgery, Division of General Thoracic Surgery, Protestant Hospital of Bethel Foundation, Burgsteig 13, 33617, Bielefeld, Germany.

Department of Cell Biology, University of Bielefeld, Bielefeld, Germany.

出版信息

Gen Thorac Cardiovasc Surg. 2021 Feb;69(2):371-374. doi: 10.1007/s11748-020-01445-9. Epub 2020 Jul 28.

Abstract

A 27-year-old male patient presented with cough and right-sided, light thoracic pain. His physical appearance showed typical features of gigantism. Subsequently, further diagnostic work-up showed elevated level of growth hormone and a huge tumor of the right lung, identifying a typical pulmonary carcinoid tumor (TPCT). Curative surgery was performed leading to normalization of the elevated growth hormone levels few days after surgery. Two- and five-year follow-up showed no signs of recurrence. Respected to tumor size, we determined the largest TPCT to be reported in medical literature history.

摘要

一位 27 岁男性患者以咳嗽和右侧轻度胸痛为主诉就诊。他的外貌表现出典型的巨人症特征。进一步的诊断检查显示生长激素水平升高,右侧肺部有一个巨大的肿瘤,诊断为典型的肺类癌肿瘤(TPCT)。施行根治性手术,术后几天内升高的生长激素水平恢复正常。术后两年和五年的随访均未发现复发迹象。根据肿瘤大小,我们确定这是文献中报道的最大的 TPCT。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c433/7868318/1c26f358788d/11748_2020_1445_Fig1_HTML.jpg

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