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急性A型主动脉夹层:哪些诊断方式仍可用于手术指征?

Acute type-A dissection of the aorta: which diagnostic modes remain for surgical indication?

作者信息

Laas J, Schlüter G, Daniel W, Hendrickx P, Haverich A

机构信息

Department of Surgery, Hannover Medical School, Federal Republic of Germany.

出版信息

Eur J Cardiothorac Surg. 1987;1(3):169-72. doi: 10.1016/1010-7940(87)90035-2.

DOI:10.1016/1010-7940(87)90035-2
PMID:3272808
Abstract

The natural course of acute type-A dissection of the aorta (AADA) implies a mortality of 50% within the initial 2 days. Preoperative diagnostic tests have to be expeditious while avoiding hypertension and direct manipulation of the aneurysm to prevent aortic rupture. Since 1979, 51 patients have been operated upon for AADA. The diagnosis was established by one or more of the following methods: transthoracic echocardiography (TTE); transesophageal echocardiography (TEE); conventional angiography (CA); intravenous digital subtraction angiography (DSA); and computed tomography with bolus injection of contrast medium (CT). TTE (n = 26) showed a dissection in 72%, suggested an intimal flap in 25%, and missed the diagnosis in 1 case. CT (n = 15) and DSA (n = 10) failed to indicate dissection in 1 case each. CA (n = 27) demonstrated dissection in every case but was the most time-consuming and stressful method. Since the introduction of combined transthoracic and transesophageal echocardiography, no other diagnostic methods have been used. On the basis of this experience, we propose the following diagnostic plan: 1. in AADA, the demonstration of an intimal flap in the ascending aorta by TTE/TEE is an indication for immediate surgery without further diagnostic measures (10 patients: no false-positive findings); 2. if a dissection is suggested by TTE/TEE, then DSA is performed if the supra-aortic branches are suspected to be compromised; CT is preferred if an extrapericardial aortic rupture is suspected; 3. the time-consuming and stressful diagnostic approach of conventional angiography is no longer indicated.

摘要

急性A型主动脉夹层(AADA)的自然病程意味着在最初2天内死亡率为50%。术前诊断检查必须迅速进行,同时要避免高血压和直接触摸动脉瘤以防止主动脉破裂。自1979年以来,已有51例患者接受了AADA手术。诊断通过以下一种或多种方法确定:经胸超声心动图(TTE);经食管超声心动图(TEE);传统血管造影(CA);静脉数字减影血管造影(DSA);以及静脉注射造影剂的计算机断层扫描(CT)。TTE(n = 26)显示72%存在夹层,25%提示有内膜瓣,1例漏诊。CT(n = 15)和DSA(n = 10)各有1例未能显示夹层。CA(n = 27)在每例中均显示有夹层,但却是最耗时且压力最大的方法。自从引入经胸和经食管联合超声心动图后,未再使用其他诊断方法。基于这一经验,我们提出以下诊断方案:1. 在AADA中,TTE/TEE显示升主动脉有内膜瓣是立即手术的指征,无需进一步诊断措施(10例患者:无假阳性结果);2. 如果TTE/TEE提示有夹层,若怀疑主动脉弓上分支受累则进行DSA检查;若怀疑心包外主动脉破裂则首选CT检查;3. 不再采用耗时且压力大的传统血管造影诊断方法。

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