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使用POLVAD-MEV体外搏动泵进行长期双心室循环支持。单中心经验。

Long-term biventricular circulatory support with POLVAD-MEV paracorporeal pulsatile pumps. Single-centre experience.

作者信息

Urbanowicz Tomasz K, Baszyńska-Wachowiak Hanna, Olasińska-Wiśniewska Anna, Misterski Marcin, Stefaniak Sebastian, Ligowski Marcin, Jemielity Marek

机构信息

Department of Cardiac Surgery and Transplantology, Poznan University of Medical Sciences, Poznan, Poland.

出版信息

Kardiochir Torakochirurgia Pol. 2020 Jun;17(2):101-104. doi: 10.5114/kitp.2020.97269. Epub 2020 Jul 20.

Abstract

INTRODUCTION

Severe heart failure decompensation requires circulatory mechanical support in emergency situations. Polish paracorporeal pulsatile pumps, POLVAD-MEV, are designed for biventricular end-stage heart dysfunction.

AIM

To evaluate long-term POLVAD-MEV therapy by multiple pump exchange in patients on a transplant list.

MATERIAL AND METHODS

There were 3 patients in INTERMACS level 1 referred for emergency POLVAD-MED implantation due to acute heart failure deterioration. The paracorporeal pulsatile mechanical support was applied due to severe biventricular dysfunction.

RESULTS

They were supported by paracorporeal biventricular POLVAD-MEV pumps for 438, 473 and 394 days until heart transplantation. During the hospitalisation the pumps required multiple pumps exchanges within 29 ±10 (4-49) day intervals.

CONCLUSIONS

POLVAD-MEV paracorporeal pulsatile pumps present a safe option for long-term circulatory support in a selected group of patients. Therapy requires pump exchange but enables survival while awaiting a heart transplant.

摘要

引言

严重心力衰竭失代偿在紧急情况下需要循环机械支持。波兰体外搏动泵POLVAD-MEV专为双心室终末期心脏功能障碍设计。

目的

通过在等待移植名单上的患者中进行多次泵更换来评估POLVAD-MEV的长期治疗效果。

材料与方法

有3例INTERMACS 1级患者因急性心力衰竭恶化而转诊接受紧急POLVAD-MED植入。由于严重的双心室功能障碍,采用了体外搏动机械支持。

结果

他们在接受心脏移植前,由体外双心室POLVAD-MEV泵支持了438天、473天和394天。住院期间,泵需要在29±10(4-49)天的间隔内进行多次泵更换。

结论

POLVAD-MEV体外搏动泵为特定患者群体的长期循环支持提供了一种安全选择。治疗需要进行泵更换,但能使患者在等待心脏移植期间存活。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a5e/7379227/28ba3388725f/KITP-17-41319-g001.jpg

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