Sumi Y, Ueda M, Kaneda T, Oka T, Torii S
Department of Oral Surgery, School of Medicine, Nagoya University, Japan.
Ann Plast Surg. 1986 Jan;16(1):68-74. doi: 10.1097/00000637-198601000-00007.
The changes of vascular patterns in pedicle skin flaps were studied in rats at various intervals after operation using microangiography, with the following results: (1) Vascular change was observed in the marginal area of the flap after operation, possibly related to the release of an angiogenic factor during anaerobic metabolism. (2) Both primary and secondary revascularization were observed in the flap, but the main process was found to be primary revascularization. (3) Four days after operation, revascularization was observed. (4) Longitudinal rearrangement of the vessels in the flap could not be observed. (5) At sutured areas where the stitches remained, severe vascular reaction continued for a longer period.
利用微血管造影术,在术后不同时间段对大鼠带蒂皮瓣的血管模式变化进行了研究,结果如下:(1)术后在皮瓣边缘区域观察到血管变化,这可能与无氧代谢过程中血管生成因子的释放有关。(2)在皮瓣中观察到了原发性和继发性血管再生,但发现主要过程是原发性血管再生。(3)术后四天观察到血管再生。(4)未观察到皮瓣内血管的纵向重排。(5)在缝线留存的缝合区域,严重的血管反应持续较长时间。