Kanesan Nithya, Mohamad Irfan, Mohamad Umbaik Norsyamira Aida, Zawawi Norzaliana
Universiti Sains Malaysia, Health Campus, School of Medical Sciences, Department of Otorhinolaryngology-Head and Neck Surgery, Kelantan, Malaysia.
Universiti Sains Malaysia Health Campus, School of Medical Sciences, Department of Otorhinolaryngology-Head and Neck Surgery, Kelantan, Malaysia.
Medeni Med J. 2020;35(2):166-169. doi: 10.5222/MMJ.2020.82956. Epub 2020 Jun 30.
Carcinosarcoma is a rare type of malignant tumour that possess both the elements of carcinoma and sarcoma. They may occur in various locations such as the uterus, breast, thyroid, lung and gastrointestinal system. However, very few primary mediastinal carcinosarcomas have been reported. We are presenting a case of a 75-year-old male who presented with progressive dysphagia and hoarseness for 3 weeks. Contrast-enhanced computed tomography of the neck showed features of enlarged mediastinal necrotic nodes and the biopsy of this mass showed morphology and immunohistochemical profile that are consistent with carcinosarcoma. However, the patient succumbed to his illness soon after diagnosis.
癌肉瘤是一种罕见的恶性肿瘤，兼具癌和肉瘤两种成分。它们可发生于身体的各个部位，如子宫、乳腺、甲状腺、肺及胃肠道系统。然而，原发性纵隔癌肉瘤的报道却极为罕见。我们在此报告一例75岁男性患者，其出现进行性吞咽困难和声音嘶哑3周。颈部增强计算机断层扫描显示纵隔坏死淋巴结肿大，对该肿物进行活检，其形态学及免疫组化特征均符合癌肉瘤。然而，患者在确诊后不久便因病去世。
