Veiga-Canuto D, Carreres-Polo J
Residente de radiología de cuarto año, Hospital Universitari i Politècnic La Fe, València, España.
Facultativo especialista en radiología y miembro de la sección de Neurorradiología, Hospital Universitari i Politècnic La Fe, València, España.
Radiologia (Engl Ed). 2020 Sep-Oct;62(5):400-410. doi: 10.1016/j.rx.2020.05.007. Epub 2020 Jul 28.
Pseudotumor cerebri is a disorder characterized by increased intracranial pressure that predominantly affects obese young women. This paper aims to define the concepts of primary pseudotumor cerebri, in which the cause cannot be identified (also known as idiopathic intracranial hypertension), and secondary pseudotumor cerebri, in which the cause can be identified. We review the current role of imaging techniques in diagnosing pseudotumor cerebri and describe and illustrate the most characteristic imaging findings of the disorder, some of which are included in the diagnostic criteria proposed in 2013. We also consider the fundamental role of interventional radiology in the treatment of pseudotumor cerebri because placing a stent in stenosed venous sinuses is a novel treatment option in patients who are refractory to classical treatment. Finally, we describe the imaging biomarkers that have been evaluated for diagnosing primary pseudotumor cerebri and predicting the response to treatment.
假性脑瘤是一种以颅内压升高为特征的疾病,主要影响肥胖的年轻女性。本文旨在明确原发性假性脑瘤(病因不明,也称为特发性颅内高压)和继发性假性脑瘤(病因可明确)的概念。我们回顾了成像技术在诊断假性脑瘤中的当前作用,并描述和展示了该疾病最具特征性的成像表现,其中一些被纳入了2013年提出的诊断标准。我们还考虑了介入放射学在假性脑瘤治疗中的重要作用,因为在狭窄的静脉窦中放置支架是对传统治疗难治的患者的一种新的治疗选择。最后,我们描述了已被评估用于诊断原发性假性脑瘤和预测治疗反应的成像生物标志物。