Department of Anesthesiology and Pain Medicine, Mount Sinai Hospital, University of Toronto, Canada.
Division of Cardiology, Pregnancy and Heart Disease Program, Department of Medicine, Mount Sinai Hospital, University of Toronto, Canada.
Int J Obstet Anesth. 2020 Nov;44:40-50. doi: 10.1016/j.ijoa.2020.06.001. Epub 2020 Jun 24.
The incidence of heart failure among pregnant women with pre-existing cardiac disease is quoted as 13%, with 10% requiring hospitalization. There is limited literature on heart failure in the pregnant population. The study objective was to describe the etiology and management of women hospitalized in our institution for heart failure during pregnancy.
A retrospective cohort study investigated women who presented with heart failure in pregnancy between 2004 and 2017. Hospital records were interrogated using International Classification of Diseases v10 codes for heart failure. Patient characteristics, investigations, treatment, obstetric and anesthetic management, and maternal-fetal outcome data were collected and summarized using descriptive statistics.
One-hundred-and-twenty cases (in 93 122 deliveries) were identified across the 13-year period (antepartum heart failure 51%, postpartum heart failure 49%).The most common etiologies were pre-eclampsia (28%), cardiomyopathy (22%), and valvular heart disease (18%). Cesarean delivery occurred in 76% of cases (13% because of the maternal cardiac condition). Neuraxial techniques were used for most deliveries (cesarean 83%; vaginal 90%). For cesarean delivery, titrated epidural or general anesthesia was employed in 48% and 16%, respectively. Cardiac arrest occurred in two cases (1.7%) and 44% required coronary or intensive care unit admission.
The incidence of heart failure was 0.13% (1:776 deliveries). Pre-eclampsia was the leading cause but may have been historically under-acknowledged. Anesthetic and obstetrical decisions were tailored by means of multidisciplinary input, with cesarean delivery and regional anesthesia used in the majority. The postpartum period warrants heightened attention for these patients.
患有基础心脏疾病的孕妇心力衰竭的发病率为 13%,其中 10%需要住院治疗。关于妊娠人群心力衰竭的文献有限。本研究旨在描述我院妊娠期间因心力衰竭住院的女性的病因和治疗方法。
采用回顾性队列研究,调查了 2004 年至 2017 年间因心力衰竭在妊娠期间住院的女性。使用国际疾病分类第 10 版心力衰竭代码对住院记录进行了查询。收集并总结了患者特征、检查、治疗、产科和麻醉管理以及母婴结局数据,并采用描述性统计方法进行了总结。
在 13 年期间共发现 120 例(93122 例分娩)患者(产前心力衰竭占 51%,产后心力衰竭占 49%)。最常见的病因是子痫前期(28%)、心肌病(22%)和瓣膜性心脏病(18%)。76%的病例行剖宫产术(13%因母亲心脏状况而行剖宫产术)。大多数分娩采用了脊麻技术(剖宫产术 83%;阴道分娩 90%)。对于剖宫产术,分别有 48%和 16%使用了滴定硬膜外或全身麻醉。有 2 例(1.7%)发生心脏骤停,44%需要行冠状动脉或重症监护病房治疗。
心力衰竭的发病率为 0.13%(1:776 例分娩)。子痫前期是主要病因,但可能在历史上被低估了。麻醉和产科决策是通过多学科的投入进行调整的,大多数患者采用了剖宫产术和区域麻醉。这些患者在产后期间需要更加密切的关注。