From the Department of surgery, Medical College of Wisconsin, Milwaukee, Wisconsin.
Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin.
ASAIO J. 2020 Aug;66(8):915-921. doi: 10.1097/MAT.0000000000001099.
A right ventricular assist device (RVAD) using a dual-lumen percutaneous cannula inserted through the right internal jugular vein (IJV) might improve weaning in patients with refractory right ventricular (RV) failure. However, the reported experience with this cannula is limited. We reviewed the records of all patients receiving RVAD support with this new dual-lumen cannula at our institution between April 2017 and February 2019. We recorded data on weaning, mortality, and device-specific complications. We compared outcomes among three subgroups based on the indications for RVAD support (postcardiotomy, cardiogenic shock, and primary respiratory failure) and against similar results in the literature. Mean (standard deviation [SD]) age of the 40 patients (29 men) was 53 (15.5) years. Indications for implantation were postcardiotomy support in 18 patients, cardiogenic shock in 12, and respiratory failure in 10. In all, 17 (94%) patients in the postcardiotomy group were weaned from RVAD support, five (42%) in the cardiogenic shock group, and seven (70%) in the respiratory failure group, overall higher than those reported in the literature (49% to 59%) for surgically placed RVADs. Whereas published in-hospital mortality rates range from 42% to 50% for surgically placed RVADs and from 41% to 50% for RVADs with percutaneous cannulas implanted through the right IJV, mortality was 11%, 58%, and 40% in our subgroups, respectively. There were no major device-related complications. This percutaneous dual-lumen cannula appears to be safe and effective for managing refractory RV failure, with improved weaning and mortality profile, and with limited device-specific adverse events.
经右颈内静脉(IJV)插入双腔经皮导管的右心室辅助装置(RVAD)可能有助于改善难治性右心室(RV)衰竭患者的撤机。然而,该导管的应用经验有限。我们回顾了 2017 年 4 月至 2019 年 2 月期间我院接受这种新型双腔导管 RVAD 支持的所有患者的记录。我们记录了撤机、死亡率和器械相关并发症的数据。我们根据 RVAD 支持的适应证(心脏手术后、心源性休克和原发性呼吸衰竭)将结果与文献中的相似结果进行了比较,并将结果分为三个亚组。40 例患者(29 例男性)的平均(标准差[SD])年龄为 53(15.5)岁。植入的适应证为 18 例心脏手术后支持、12 例心源性休克和 10 例呼吸衰竭。在心脏手术后组中,17(94%)例患者成功撤机 RVAD 支持,心源性休克组 5(42%)例,呼吸衰竭组 7(70%)例,均高于文献报道的外科放置 RVAD 组的撤机率(49%至 59%)。虽然外科放置 RVAD 的住院死亡率范围为 42%至 50%,经右 IJV 植入经皮导管的 RVAD 死亡率范围为 41%至 50%,但我们的亚组分别为 11%、58%和 40%。没有发生重大器械相关并发症。这种经皮双腔导管似乎安全有效,可用于治疗难治性 RV 衰竭,撤机效果和死亡率改善,且器械相关不良事件有限。