Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.
Faculty of Medicine, Lebanese University, Beirut, Lebanon.
Lupus. 2020 Oct;29(12):1493-1502. doi: 10.1177/0961203320947152. Epub 2020 Aug 2.
Prior to 1983, several landmark reports prepared the stage for a detailed description of the Antiphospholipid (Hughes) syndrome (APS). Formerly depicted as lupus-like, APS exhibits a wide spectrum of symptoms that overlap with Sjogren's, Hashimoto, and other autoimmune diseases. In this review, we take a glimpse into the history of description of APS, discussing the events that led to its recognition as one of the most common autoimmune diseases and the enormous impact of that recognition in the rheumatology field.
在 1983 年之前，有几项具有里程碑意义的报告为详细描述抗磷脂（休斯）综合征（APS）奠定了基础。APS 以前被描述为狼疮样，表现出广泛的症状，与干燥综合征、桥本氏甲状腺炎和其他自身免疫性疾病重叠。在这篇综述中，我们简要回顾了 APS 的描述历史，讨论了导致其被认为是最常见的自身免疫性疾病之一的事件，以及这一认识在风湿病领域产生的巨大影响。
