Freland C
Pathol Biol (Paris). 1977 May;25(5):345-52.
Erysipelothrix rhusiopathiae is widely distributed in nature (animal, soil). It is commonly known as the causative agent of cutaneous lesions called "erysipeloid of Rosenbach". Only 31 cases of bacterial endocarditis have been reported in the literature. The etiologic diagnosis of Esysipelothrix infection was established by the presence of bacteria in blood cultures or heart-valve cultures. Immunological study is unusual owing to the rapid course of the infection. The histologic observation of heart lesions corroborates the diagnosis. The patient's receptivity depends on his occupation, general health (importance of rheumatic heart disease), sex (male), age (from 40 to 60 years old), but also on the season (from July to October) and climate (temperate). With the exception of the few cases where it is possible to recognize a portal of entry of infection or the appearance of typical cutaneous manifestations, bacterial endocarditis due to Erysipelothrix presents a clinical picture similar to that of most other bacterial endocarditis. The antibiotic treatment is an association of penicillin-streptomycin, administered in large doses over a period of at least four weeks. In spite of intensive therapy, many patients died.
猪红斑丹毒丝菌在自然界(动物、土壤)中广泛分布。它通常被认为是导致“罗森巴赫类丹毒”皮肤损伤的病原体。文献中仅报道了31例细菌性心内膜炎病例。通过血培养或心脏瓣膜培养中发现细菌来确立猪红斑丹毒丝菌感染的病因诊断。由于感染病程进展迅速,免疫学研究并不常见。心脏病变的组织学观察证实了诊断。患者的易感性取决于其职业、总体健康状况(风湿性心脏病的重要性)、性别(男性)、年龄(40至60岁),还取决于季节(7月至10月)和气候(温带)。除了少数能够识别感染入口或典型皮肤表现出现的病例外,猪红斑丹毒丝菌引起的细菌性心内膜炎的临床表现与大多数其他细菌性心内膜炎相似。抗生素治疗是青霉素 - 链霉素联合使用,大剂量给药至少四周。尽管进行了强化治疗,许多患者仍死亡。