241876Joint Pathology Center, Silver Spring, MD, USA.
8789University of California Davis, CA, USA.
Vet Pathol. 2020 Nov;57(6):885-888. doi: 10.1177/0300985820943536. Epub 2020 Aug 3.
Four captive, lesser hedgehog tenrecs () were euthanized for soft bones that prevented normal mastication and/or ambulation. Antemortem radiographs (available in 2 cases) revealed osteopenia. Antemortem bloodwork (available in 2 cases) revealed hypophosphatemia. Dietary history (available in 2 cases) indicated the animals were eating only insects. Histologically, all examined bones had wide osteoid seams that caused expansion of the cortices. Osteoid deposition was exuberant and it partially filled marrow cavities (hyperostosis). Nondecalcified sections of bone (available in 2 cases) revealed that osteoid was poorly mineralized, consistent with osteomalacia. Insects are poor dietary sources of vitamin D, and dietary vitamin D deficiency is considered the most likely cause for metabolic bone disease in these animals.
四只圈养的小刺猬豪猪（）因骨骼变软而无法正常咀嚼和/或行走，被实施安乐死。生前的射线照片（在 2 例中可用）显示骨质疏松症。生前的血液检查（在 2 例中可用）显示血磷酸盐过少。饮食史（在 2 例中可用）表明这些动物只吃昆虫。组织学检查显示，所有检查的骨骼都有宽大的类骨质缝，导致皮质扩张。类骨质沉积丰富，部分填满骨髓腔（骨质增生）。未脱钙的骨切片（在 2 例中可用）显示类骨质矿化不良，符合佝偻病。昆虫是维生素 D 的不良膳食来源，而饮食中维生素 D 缺乏被认为是这些动物代谢性骨病的最可能原因。
