Ekici Aydanur, Ekici Mehmet, İleri Şule, Çimen Asiye Büşra, Aslan Habibe
Department of Pulmonary Diseases, Faculty of Medicine, Kirikkale University, Kirikkale, Turkey.
Clin Respir J. 2020 Nov;14(11):1099-1104. doi: 10.1111/crj.13241. Epub 2020 Aug 13.
Obesity-hypoventilation syndrome occurs with alveolar hypoventilation during sleeping and daytime. Obesity may be a risk factor for venous thromboembolism. However, the venous thromboembolism in the obesity-hypoventilation syndrome is not well characterized.
This case series aimed to investigate the presence and clinical features of venous thromboembolism in patients with the obesity-hypoventilation syndrome.
Data of eight case reports were collected. Ages ranged from 36 to 73 years.
All patients had mosaic perfusion and enlarged main pulmonary artery, two had signs of infarction and mostly segmental and subsegmental filling defects. On the basis of this information some conclusions can be drawn carefully.
Present cases indicate that pulmonary embolism are also very common in patients with obesity-hypoventilation syndrome, anticoagulant therapy is at least as important as the treatment of the current disease. Clinicians will frequently be faced with patients with obesity-hypoventilation syndrome suspected of PE.
肥胖低通气综合征在睡眠和日间均伴有肺泡低通气。肥胖可能是静脉血栓栓塞的一个危险因素。然而，肥胖低通气综合征中的静脉血栓栓塞情况尚未得到充分描述。
本病例系列旨在调查肥胖低通气综合征患者静脉血栓栓塞的存在情况及临床特征。
收集了8例病例报告的数据。年龄范围为36至73岁。
所有患者均有马赛克灌注及主肺动脉增宽，2例有梗死征象，主要为节段性和亚节段性充盈缺损。基于这些信息可谨慎得出一些结论。
目前的病例表明，肺栓塞在肥胖低通气综合征患者中也非常常见，抗凝治疗至少与当前疾病的治疗同样重要。临床医生将经常面对疑似肺栓塞的肥胖低通气综合征患者。
