Faculty of Medicine, Department of Radiology, Medical Physics, Medical Center-University of Freiburg, Freiburg, Germany.
Magn Reson Med. 2021 Feb;85(2):1123-1133. doi: 10.1002/mrm.28444. Epub 2020 Aug 3.
Nuclear Magnetic Resonance field probes provide exciting possibilities for enhancing MR image quality by allowing for calibration of k-space trajectories and/or dynamic measurement of local field changes. The purpose of this study is to design and build field probes, which are easier to manufacture and more flexible to use than existing probes.
A new manufacturing method is presented based on light-activated resin to encase the coil assembly and the 1H sample. This method allows for realizing field probes with tightly integrated orthogonal coils, whereby the local resonance frequency of protons can be adjusted during the MR experiment, by applying a DC current to the integrated -field modification coil.
The apparent field probe position in a gradient echo experiment was shifted within the field of view by changing its Larmor frequency using an integrated micro-coil with 5.5 windings. The measured frequency modulation induced by the -field modification coil was 113 Hz/mA. The probe was tested with currents up to 100 mA. The DC current in the local field modification coil did not introduce visible artifacts in the MR images. Furthermore selective off-resonant excitation of the new field probes at 2 kHz above the main RF frequency was demonstrated. Gradient impulse response functions measured with a traditional and proposed probe show similar gradient imperfections.
The presented approach opens up new possibilities for concurrent field monitoring during MR experiments using standard RF capabilities of clinical scanners.
磁共振(MR)磁场探头通过允许对 K 空间轨迹进行校准和/或对局部磁场变化进行动态测量,为提高 MR 图像质量提供了令人兴奋的可能性。本研究的目的是设计和制造比现有探头更容易制造且更灵活的磁场探头。
提出了一种新的制造方法,该方法基于光激活树脂来封装线圈组件和 1H 样品。这种方法可以实现具有紧密集成正交线圈的磁场探头,通过向集成的 - 场修正线圈施加直流电流,可以在 MR 实验期间调整质子的局部共振频率。
通过使用带有 5.5 匝的集成微线圈改变其拉莫尔频率,在梯度回波实验中改变了明显的磁场探头位置。 - 场修正线圈引起的测量频率调制为 113 Hz/mA。该探头在高达 100 mA 的电流下进行了测试。在 MR 图像中,局部磁场修正线圈中的直流电流没有引入可见的伪影。此外,还证明了在主 RF 频率上方 2 kHz 的新磁场探头的选择性离共振激发。使用传统和提出的探头测量的梯度脉冲响应函数显示出相似的梯度不完美。
所提出的方法为使用临床扫描仪的标准 RF 功能在 MR 实验期间进行同时的场监测开辟了新的可能性。