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Gene Therapy for Respiratory Diseases: Progress and a Changing Context.

作者信息

Alton Eric W F W, Boyd A Christopher, Davies Jane C, Gill Deborah R, Griesenbach Uta, Harman Tracy E, Hyde Stephen, McLachlan Gerry

机构信息

Gene Therapy Group, National Heart and Lung Institute, Imperial College London, London, United Kingdom.

UK CF Gene Therapy Consortium, London, United Kingdom.

出版信息

Hum Gene Ther. 2020 Sep;31(17-18):911-916. doi: 10.1089/hum.2020.142.

DOI:10.1089/hum.2020.142
PMID:32746737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7499889/
Abstract
摘要

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J Cyst Fibros. 2020 Sep;19(5):688-695. doi: 10.1016/j.jcf.2020.05.012. Epub 2020 Jun 8.
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Chimeric antigen receptor T cell therapy comes to clinical practice.嵌合抗原受体 T 细胞疗法走向临床实践。
Curr Oncol. 2020 Apr;27(Suppl 2):S115-S123. doi: 10.3747/co.27.5283. Epub 2020 Apr 1.
3
Development of Large-Scale Downstream Processing for Lentiviral Vectors.慢病毒载体大规模下游处理技术的发展
Mol Ther Methods Clin Dev. 2020 Mar 30;17:717-730. doi: 10.1016/j.omtm.2020.03.025. eCollection 2020 Jun 12.
4
Impact of CFTR modulator use on outcomes in people with severe cystic fibrosis lung disease.CFTR 调节剂治疗对严重肺囊性纤维化患者结局的影响。
Eur Respir Rev. 2020 Mar 20;29(155). doi: 10.1183/16000617.0112-2019. Print 2020 Mar 31.
5
Immune Responses to Viral Gene Therapy Vectors.病毒基因治疗载体的免疫反应。
Mol Ther. 2020 Mar 4;28(3):709-722. doi: 10.1016/j.ymthe.2020.01.001. Epub 2020 Jan 10.
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Gene therapy for severe combined immunodeficiencies and beyond.基因治疗重度联合免疫缺陷病及其他疾病。
J Exp Med. 2020 Jan 6;217(2). doi: 10.1084/jem.20190607.
7
Integrating the multiple breath washout test into international multicentre trials.将多次呼吸冲洗试验纳入国际多中心试验。
J Cyst Fibros. 2020 Jul;19(4):602-607. doi: 10.1016/j.jcf.2019.11.006. Epub 2019 Nov 24.
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Insights into the variability of nasal potential difference, a biomarker of CFTR activity.鼻腔电位差变化的洞察，CFTR 活性的生物标志物。
J Cyst Fibros. 2020 Jul;19(4):620-626. doi: 10.1016/j.jcf.2019.09.015. Epub 2019 Nov 4.
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Stem Cell Investig. 2019 Aug 16;6:22. doi: 10.21037/sci.2019.06.09. eCollection 2019.