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腹壁子宫内膜异位症与韧带样瘤——具有挑战性的鉴别诊断。

Abdominal wall endometriosis versus desmoid tumor - a challenging differential diagnosis.

机构信息

Department of Ophthalmology, Department of Obstetrics and Gynecology, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, Iaşi, Romania;

出版信息

Rom J Morphol Embryol. 2020;61(1):45-50. doi: 10.47162/RJME.61.1.05.

Abstract

Abdominal wall endometriosis (AWE) in young women, with previous gynecological abdominal surgery, is the first condition considered by many practitioners when a tumor in the region of the scar appears. AWE seems to be caused by an iatrogenic transfer of endometrial cells at the level of the scar. The onset of the disease may be late in many cases. Despite the fact that the disease could be totally asymptomatic, there are certain risk factors that can be identified during the anamnesis, such as: heredity, menarche at the age of >14 years, menstrual cycle <27 days, delayed menopause, excessive alcohol and caffeine consumption. Suggestive signs include cyclic or continuous abdominal pain caused by a palpable abdominal wall mass with a maximum tenderness in the region of the surgical scar. The differential diagnosis is complex and rare entities like desmoid tumors (DTs) must be taken into consideration. Desmoid tumor, or the so-called aggressive fibromatosis (AF), is a rare fibroblastic proliferation. This tumor can develop in any muscular aponeurotic structure of the body and is considered benign but with a high recurrence rate. DTs can cause local infiltration, subsequently producing certain levels of deformity and potential obstruction of vital structures and organs. The differential diagnosis is challenging in this situations, the imagery exams are useful, especially in detecting the precise location of the tumor. The histological examination of the tumor can state the final and precise diagnosis.

摘要

腹壁子宫内膜异位症(AWE)在有妇科腹部手术史的年轻女性中,当疤痕区域出现肿瘤时,许多医生首先考虑的就是这种疾病。AWE 似乎是由疤痕处的子宫内膜细胞医源性转移引起的。在许多情况下,疾病可能会很晚才出现。尽管这种疾病可能完全没有症状,但在病史中可以识别出某些危险因素,例如:遗传、初潮年龄 >14 岁、月经周期 <27 天、绝经延迟、过度饮酒和咖啡因摄入。提示性的迹象包括由可触及的腹壁肿块引起的周期性或持续性腹痛,最大压痛位于手术疤痕区域。鉴别诊断很复杂,必须考虑到罕见的实体,如韧带样瘤(DTs)。韧带样瘤,或所谓的侵袭性纤维瘤病(AF),是一种罕见的成纤维细胞增生。这种肿瘤可以发生在身体的任何肌肉腱膜结构中,被认为是良性的,但复发率很高。DTs 可引起局部浸润,随后产生一定程度的畸形和潜在的重要结构和器官阻塞。在这种情况下,鉴别诊断具有挑战性,影像学检查很有用,尤其是在检测肿瘤的精确位置。肿瘤的组织学检查可以做出最终和准确的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62fe/7728103/63abf937be25/RJME-61-1-45-fig1.jpg

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