J Opt Soc Am A Opt Image Sci Vis. 2020 Aug 1;37(8):1249-1256. doi: 10.1364/JOSAA.394985.
A handheld near-infrared optical scanner (NIROS) was recently developed to map for effective changes in oxy- and deoxyhemoglobin concentration in diabetic foot ulcers (DFUs) across weeks of treatment. Herein, a coregistration and image segmentation approach was implemented to overlay hemoglobin maps onto the white light images of ulcers. Validation studies demonstrated over 97% accuracy in coregistration. Coregistration was further applied to a healing DFU across weeks of healing. The potential to predict changes in wound healing was observed when comparing the coregistered and segmented hemoglobin concentration area maps to the visual area of the wound.
最近开发了一种手持式近红外光学扫描仪（NIROS），用于在数周的治疗过程中绘制糖尿病足溃疡（DFU）中氧合和脱氧血红蛋白浓度的有效变化图。在此，实施了一种配准和图像分割方法，将血红蛋白图叠加到溃疡的白光图像上。验证研究表明配准的准确率超过 97%。进一步将配准应用于愈合的 DFU 数周的愈合过程。通过将配准和分割的血红蛋白浓度区域图与伤口的视觉区域进行比较，观察到了预测伤口愈合变化的潜力。
