Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden.
Department of Surgery, Skåne University Hospital, Lund University, Malmö, Sweden.
PLoS One. 2020 Aug 5;15(8):e0236799. doi: 10.1371/journal.pone.0236799. eCollection 2020.
Numerous prior studies, even from countries with free access to care, have associated long travel time to care with poor survival in patients with colorectal cancer.
This is a data-linkage study of all 3718 patients with colorectal cancer, diagnosed between 2007 and 2013 in Northern Sweden, one of the most sparsely populated areas in Europe. Travel time to nearest hospital was calculated based on GPS coordinates and multivariable Cox regression was used to analyse possible associations between travel time and cause-specific survival.
No association between travel time and survival was observed, either in univariable analysis (colon HR 1.00 [95% CI 0.998-1.003]; rectal HR 0.998; [95% CI 0.995-1.002]) or in multivariable Cox regression analysis (colon HR 0.999 [95% CI 0.997-1.002]; rectal HR 0.997 [95% CI 0.992-1.002]).
In contrast to most other studies, no association between travel time and colorectal cancer survival was found; despite that longer travel time was associated with known risk factors for poorer outcome. In the Swedish health care setting, travel time does not appear to represent a barrier to care or to negatively influence outcomes.
许多先前的研究,甚至来自于医疗服务可自由获取的国家,都将就医的长途旅行时间与结直肠癌患者的不良生存结果联系起来。
这是一项对瑞典北部 2007 年至 2013 年间诊断出的 3718 例结直肠癌患者进行的数据链接研究,瑞典北部是欧洲人口最稀少的地区之一。根据 GPS 坐标计算了到最近医院的旅行时间,并使用多变量 Cox 回归分析了旅行时间与特定原因生存之间的可能关联。
无论是在单变量分析(结肠癌 HR 1.00 [95% CI 0.998-1.003];直肠癌 HR 0.998 [95% CI 0.995-1.002])还是在多变量 Cox 回归分析中(结肠癌 HR 0.999 [95% CI 0.997-1.002];直肠癌 HR 0.997 [95% CI 0.992-1.002]),都没有发现旅行时间与生存之间存在关联。
与大多数其他研究相反,在瑞典的医疗保健环境中,旅行时间与结直肠癌的生存结果之间没有关联;尽管较长的旅行时间与已知的预后不良风险因素相关。旅行时间似乎不是护理的障碍,也不会对结果产生负面影响。