Division of Cognitive Neuroscience, University of Tabriz, Tabriz, Iran.
Psychology Department, University of Tabriz, Tabriz, Iran.
Neuropsychopharmacol Rep. 2020 Sep;40(3):254-261. doi: 10.1002/npr2.12129. Epub 2020 Aug 5.
Verbal Fluency is sensitive to brain damage and is employed to assess language abilities like the size of vocabulary and the semantic-lexical networks' integrity and executive functioning abilities particularly inhibition, working memory, and self-monitoring. Various studies revealed oscillatory changes related to word retrieval during different tasks. However, there are not enough studies on electroencephalographic characteristics of word retrieval routes (phonological or semantic pathway) during free recall. The purpose of our study was to investigate electroencephalography power relationship with semantic and phonological word finding routes during verbal fluency.
In this within-subject study, the electroencephalography of 20 healthy participants was recorded during written category and letter fluency tasks and compared with the rest state. Absolute power of the signals in delta (1-3.5 Hz), theta (4-7.5 Hz), alpha (8-12 Hz), and beta (12.5-30 Hz) was calculated in three lobes (frontal, parietal, and temporal).
A repeated measures ANOVA showed significant interaction of condition × lobe × frequency × side (P < .001). Post hoc test for each lobe showed significant changes in the absolute power of delta, theta and beta for frontal, delta and theta for parietal, and theta and beta for temporal lobes (P-values < .05).
Searching the words by phonological entries is associated with decreased beta and increased theta in left frontal lobe. These changes are not necessary for semantic word retrieval strategy.
言语流畅性对大脑损伤敏感，用于评估语言能力，如词汇量大小、语义词汇网络的完整性和执行功能能力，特别是抑制、工作记忆和自我监控。各种研究表明，在执行不同任务时与单词检索相关的振荡变化。然而，关于自由回忆期间语音或语义词检索路径（语音或语义通路）的脑电图特征的研究还不够。我们的研究目的是研究言语流畅性期间与语义和语音词发现路径相关的脑电图功率关系。
在这项单组研究中，对 20 名健康参与者的脑电图在书面类别和字母流畅性任务期间进行了记录，并与休息状态进行了比较。在三个脑叶（额叶、顶叶和颞叶）中计算了信号的 delta（1-3.5 Hz）、theta（4-7.5 Hz）、alpha（8-12 Hz）和 beta（12.5-30 Hz）的绝对功率。
重复测量方差分析显示条件×叶×频率×侧的交互作用具有统计学意义（P < 0.001）。对每个脑叶的事后检验显示，额叶的 delta、theta 和 beta 的绝对功率、顶叶的 delta 和 theta 的绝对功率以及颞叶的 theta 和 beta 的绝对功率均有显著变化（P 值均< 0.05）。
通过语音条目搜索单词与左额叶的 beta 降低和 theta 增加有关。这些变化对于语义词检索策略不是必需的。
