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同期行冠状动脉旁路移植术和肾移植术患者的围手术期麻醉管理和临床结局。

Perioperative Anesthetic Management and Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Grafting and Kidney Transplant in the Same Session.

机构信息

Department of Anesthesiology and Reanimation, Harran University Medical Faculty, Sanliurfa, Turkey.

Department of Heart and Vascular Surgery, Medical Park Hospital, Antalya, Turkey; Department of Heart and Vascular Surgery, Bahcesehir University, Istanbul, Turkey.

出版信息

Transplant Proc. 2020 Dec;52(10):3038-3043. doi: 10.1016/j.transproceed.2020.06.034. Epub 2020 Aug 2.

Abstract

BACKGROUND

Cardiovascular disease is commonly seen in patients with end-stage renal disease (ESRD) and is a major cause of graft failure and death in patients undergoing kidney transplant.

METHODS

The retrospective study included 77 patients with ESRD who underwent combined coronary artery bypass grafting (CABG) and kidney transplant between May 2010 and September 2017.

RESULTS

The patients included 65 (84.4%) men and 12 (15.6%) women. Diabetes mellitus (DM) and hypertension (HT) were present in 71.4% and 90.9% of the patients, respectively. Mean postoperative intensive care unit (ICU) stay was 3.4 ± 1.6 days, mean time to extubation was 12.1 ± 3.7 hours, and mean hospital stay was 11.6 ± 3.5 days. In the small group with graft rejection, EF was 41.1 ± 12.3. Two patients underwent second kidney transplant, and 1 patient underwent a third kidney transplant. Mean amount of red blood cells (RBC) and fresh-frozen plasma (FFP) transfusion was 2.6 ± 0.7 and 2.1 ± 0.7 units, respectively.

CONCLUSION

The study showed that CABG and kidney transplant can be performed in a combined approach in the same session and that this combined approach is likely to have a more favorable effect on mortality and morbidity compared to the administration of these 2 surgeries in separate sessions.

摘要

背景

心血管疾病在终末期肾病(ESRD)患者中很常见,是导致接受肾移植的患者移植物失败和死亡的主要原因。

方法

本回顾性研究纳入了 2010 年 5 月至 2017 年 9 月期间行冠状动脉旁路移植术(CABG)联合肾移植的 77 例 ESRD 患者。

结果

患者包括 65 例(84.4%)男性和 12 例(15.6%)女性。糖尿病(DM)和高血压(HT)分别占 71.4%和 90.9%。术后重症监护病房(ICU)入住时间的平均值为 3.4±1.6 天,拔管时间的平均值为 12.1±3.7 小时,住院时间的平均值为 11.6±3.5 天。在发生移植物排斥反应的小样本中,EF 为 41.1±12.3。2 例患者接受了第二次肾移植,1 例患者接受了第三次肾移植。平均红细胞(RBC)和新鲜冷冻血浆(FFP)输注量分别为 2.6±0.7 和 2.1±0.7 单位。

结论

研究表明,CABG 和肾移植可以在同一时间联合进行,与分两次进行这两种手术相比,这种联合方法可能对死亡率和发病率有更有利的影响。

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