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肾移植后的心血管手术——适应证、并发症及结局

Cardiovascular surgery after renal transplantation--indications, complications and outcome.

作者信息

Basic-Jukic Nikolina, Ivanac-Jankovic Renata, Biocina Bojan, Kes Petar

机构信息

a Department of Nephrology , Arterial Hypertension, Dialysis and Transplantation, University Hospital Centre Zagreb, School of Medicine, University of Zagreb , Zagreb , Croatia .

b Department of Internal Medicine , Bjelovar General Hospital , Bjelovar , Croatia , and.

出版信息

Ren Fail. 2015 Jul;37(6):1020-1. doi: 10.3109/0886022X.2015.1052950. Epub 2015 Sep 2.

Abstract

UNLABELLED

Cardiovascular diseases are the major cause of morbidity and mortality in renal transplant recipients. We report our experience in the treatment of patients with renal allograft who required cardiovascular surgery.

METHODS

Indications for cardiovascular surgery, postoperative complications, and outcome were recorded in a cohort of renal transplant recipients.

RESULTS

Thirteen patients, five female and eight male, aged from 46 to 75 years underwent cardiac surgery after renal transplantation at University Hospital Centre Zagreb. Isolated coronary artery bypass grafting (CABG) was performed in five patients, valve replacement in six patients, reconstruction of ascending aorta, and aortic arch in one patient as well as the extraction of tumor formation from the heart. Three patients had simultaneous CABG and valve replacement. Four patients (31%) required acute hemodialysis after the surgery and two of them continued with dialysis after discharge. Postoperative course was complicated with infections of the lower respiratory tract in two patients, pericardial tamponade, unstable sternum with bleeding from the wound, increased drainage from the chest demanding additional hemostasis, and in-stent restenosis in the previously placed stents, in one patient each. Fatal outcome occurred in two patients who underwent simultaneous valvular replacement and CABG within one month from the surgery.

CONCLUSION

In patients with functional renal allograft cardiovascular, surgery procedures are safe, but associated with increased incidence of perioperative complications, with majority of patients maintaining their graft function.

摘要

未标注

心血管疾病是肾移植受者发病和死亡的主要原因。我们报告了我们治疗需要进行心血管手术的同种异体肾移植患者的经验。

方法

记录一组肾移植受者心血管手术的指征、术后并发症及结果。

结果

在萨格勒布大学医院中心,13例患者(5例女性,8例男性,年龄46至75岁)在肾移植后接受了心脏手术。5例患者进行了单纯冠状动脉旁路移植术(CABG),6例患者进行了瓣膜置换术,1例患者进行了升主动脉和主动脉弓重建以及心脏肿瘤切除术。3例患者同时进行了CABG和瓣膜置换术。4例患者(31%)术后需要急性血液透析,其中2例出院后继续透析。术后病程出现并发症,2例患者发生下呼吸道感染,1例患者发生心包填塞,1例患者伤口出血导致胸骨不稳定,1例患者胸腔引流增加需要额外止血,1例患者先前置入的支架发生支架内再狭窄。2例在手术1个月内同时进行瓣膜置换和CABG的患者发生了致命结局。

结论

对于具有功能的同种异体肾移植心血管患者,手术操作是安全的,但围手术期并发症发生率增加,大多数患者的移植肾功能得以维持。

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