Department of Surgery, ASST Valle Olona, Gallarate Varese, Italy..
Department of Surgery, University Hospital of Ioannina & University of Ioannina, Ioannina, Greece.
Semin Oncol. 2020 Dec;47(6):355-360. doi: 10.1053/j.seminoncol.2020.07.003. Epub 2020 Jul 25.
Neoadjuvant therapy for locally advanced gastric cancer is a treatment option well recognized in international guidelines. However, neither completed randomized trials nor ongoing studies (will) offer definitive answers about the efficacy of neoadjuvant therapy. With extensive experience confirming the safety and some efficacy for this approach most current studies are focused on identifying the best preoperative treatment regimen. We try to clarify if is really the time to slow down the enthusiasm about neoadjuvant approach.
新辅助治疗局部进展期胃癌在国际指南中得到广泛认可。然而，无论是已完成的随机试验还是正在进行的研究都无法提供关于新辅助治疗疗效的明确答案。大量经验证实了这种方法的安全性和一定疗效，因此目前大多数研究都集中在确定最佳术前治疗方案上。我们试图阐明现在是否真的应该放缓对新辅助治疗方法的热情。
