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移植对医疗保险终末期肾病项目的影响。

Effect of transplantation on the Medicare end-stage renal disease program.

作者信息

Eggers P W

机构信息

Office of Research, Health Care Financing Administration, Baltimore, MD 21207.

出版信息

N Engl J Med. 1988 Jan 28;318(4):223-9. doi: 10.1056/NEJM198801283180406.

Abstract

The Medicare end-stage renal disease program has received considerable attention as a model of government funding for high-cost medical treatment. This paper examines how the program has been influenced by renal transplantation. In the past decade, the number of kidney transplantations has increased substantially, and the success rate of these procedures has improved. From 1980 to 1985, the number of transplantations increased by 10 percent per year. During that time, the survival rates for grafts from cadavers and living related donors increased by 7 and 3 percent, respectively, in part because of the introduction of cyclosporine. As a result, the fastest-growing group of beneficiaries of the Medicare end-stage renal disease program are those with functioning grafts. As of the end of 1985, these patients accounted for 18 percent of all beneficiaries and 32 percent of all beneficiaries less than 55 years of age. In the youngest groups, transplantation has reached a level sufficient to reduce the absolute numbers of patients on dialysis, beginning in 1983. Increases in transplantation are not evenly distributed among subgroups of beneficiaries. Relatively few patients 65 years of age and older receive transplants; blacks receive transplants at a rate roughly half that among whites, but the rate is increasing. Because the costs of maintaining patients with functioning grafts are only one third of those for patients on dialysis and because the quality of life is usually much better, renal transplantation is causing a convergence of the best clinical and economic outcomes for patients with end-stage renal disease.

摘要

医疗保险终末期肾病项目作为政府为高成本医疗治疗提供资金的一个典范,受到了广泛关注。本文探讨了该项目是如何受到肾移植影响的。在过去十年中,肾移植的数量大幅增加,并且这些手术的成功率也有所提高。从1980年到1985年,移植数量每年增长10%。在此期间,来自尸体供体和活体亲属供体的移植物存活率分别提高了7%和3%,部分原因是环孢素的引入。因此,医疗保险终末期肾病项目中受益增长最快的群体是那些拥有功能正常移植物的患者。截至1985年底,这些患者占所有受益人的18%,在年龄小于55岁的所有受益人中占32%。在最年轻的群体中,从1983年开始,移植数量已达到足以减少透析患者绝对数量的水平。移植的增加在受益人亚组中分布并不均匀。65岁及以上的患者接受移植的相对较少;黑人接受移植的比例大约只有白人的一半,但这一比例正在上升。由于维持有功能移植物患者的成本仅为透析患者成本的三分之一,并且由于生活质量通常要好得多,肾移植正在使终末期肾病患者在最佳临床和经济结果方面趋于一致。

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