Department of Neurology, Toho University Omori Medical Center, Japan.
Department of Neurology, Mishuku Hospital, Japan.
Intern Med. 2020 Dec 1;59(23):3085-3088. doi: 10.2169/internalmedicine.5162-20. Epub 2020 Aug 4.
The frequency and risk of embolism by Lambl's excrescences (LEs) remain unclear. We herein report an autopsy case of LEs that caused cardioembolic stroke. A 74-year-old man with colon cancer was hospitalized for ischemic stroke. His D-dimer levels were elevated. Thus, a diagnosis of ischemic stroke with Trousseau syndrome was made. At the autopsy, we found LEs in the aortic valves and thromboembolism of the brain blood vessels. This finding demonstrated that fibrin clots had adhered to the LEs because of coagulation abnormalities associated with Trousseau syndrome and became embolized. This case highlights the risk of LEs in patients with coagulation abnormalities.
Lambl 的赘生物（LE）引起栓塞的频率和风险尚不清楚。本文报告了一例由 LE 引起心源性脑栓塞的尸检病例。一名 74 岁男性，患有结肠癌，因缺血性脑卒中住院。他的 D-二聚体水平升高。因此，诊断为伴有 Trousseau 综合征的缺血性脑卒中。尸检时，我们发现主动脉瓣上有 LE 和脑血管血栓栓塞。这一发现表明，由于 Trousseau 综合征相关的凝血异常，纤维蛋白凝块已附着在 LE 上，并形成了栓子。本病例强调了凝血异常患者 LE 的风险。
