Krassioukov Andrei, Stillman Michael, Beck Lisa A
ICORD, Blusson Spinal Cord Centre, University of British Columbia, GF Strong Rehabilitation Center, Vancouver, BC, Canada.
Departments of Internal Medicine and Rehabilitation Medicine, Sydney Kimmel Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania.
Top Spinal Cord Inj Rehabil. 2020 Spring;26(2):123-127. doi: 10.46292/sci2602-123.
Spinal cord injury (SCI) disrupts the crucial "crosstalk" between the spinal autonomic nervous system and supraspinal control centers. Therefore, SCI may result not only in motor paralysis but also in potentially life-threatening impairments of many autonomic functions including, but not limited to, blood pressure regulation. Despite the detrimental consequences of autonomic dysregulation, management and recovery of autonomic functions after SCI is greatly underexplored. Although impaired autonomic function may impact several organ systems, this overview will focus primarily on disruptions of cardiovascular and thermoregulation and will offer suggestions for management of these secondary effects of SCI.
脊髓损伤(SCI)会破坏脊髓自主神经系统与脊髓上控制中心之间至关重要的“相互作用”。因此,SCI不仅可能导致运动麻痹,还可能导致许多自主功能出现危及生命的损害,包括但不限于血压调节。尽管自主神经调节异常会带来有害后果,但SCI后自主功能的管理和恢复仍未得到充分研究。虽然自主功能受损可能会影响多个器官系统,但本综述将主要关注心血管和体温调节的紊乱,并针对SCI的这些继发效应的管理提供建议。