Deschamps M M, Pape J W, Verdier R I, DeHovitz J, Thomas F, Johnson W D
Haitian Study Group on Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), Port-Au-Prince, Haiti.
Am J Gastroenterol. 1988 Jan;83(1):20-1.
We conducted a randomized prospective study to compare the efficacy of oral miconazole and ketoconazole in the treatment of candida esophagitis in acquired immune deficiency syndrome (AIDS) patients in Haiti. Twelve AIDS patients with endoscopic and microscopic diagnoses of candida esophagitis were placed on either oral miconazole or ketoconazole for 10 days. All six patients receiving oral miconazole, and four of the six receiving ketoconazole had complete resolution of their esophageal lesions at the end of treatment. We conclude oral miconazole is at least as effective as ketoconazole in the treatment of candida esophagitis in AIDS patients.
我们进行了一项随机前瞻性研究，以比较口服咪康唑和酮康唑治疗海地获得性免疫缺陷综合征（AIDS）患者念珠菌食管炎的疗效。12例经内镜和显微镜诊断为念珠菌食管炎的AIDS患者，分别接受口服咪康唑或酮康唑治疗10天。所有6例接受口服咪康唑治疗的患者，以及6例接受酮康唑治疗的患者中的4例，在治疗结束时食管病变均完全消退。我们得出结论，口服咪康唑在治疗AIDS患者念珠菌食管炎方面至少与酮康唑一样有效。
