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微波消融与经导管动脉栓塞治疗大型肝血管瘤的临床疗效

Microwave ablation versus transcatheter arterial embolization for large hepatic hemangiomas: clinical outcomes.

作者信息

Shi Yaoping, Song Jingjing, Ding Min, Tang Xiaoyin, Wang Zhi, Chi Jiachang, Wang Tao, Ji Jiansong, Zhai Bo

机构信息

Department of Interventional Oncology, School of Medicine, Renji Hospital, Shanghai Jiao-tong University, Shanghai, China.

Department of Radiology, Lishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical College, Lishui, China.

出版信息

Int J Hyperthermia. 2020;37(1):938-943. doi: 10.1080/02656736.2020.1766122.

Abstract

PURPOSE

To evaluate the safety and effect of microwave ablation (MWA) compared with transcatheter arterial embolization (TAE) for the treatment of large hepatic hemangiomas.

MATERIALS AND METHODS

A total of 135 patients with symptomatic or/and enlarging hepatic hemangiomas (5-10 cm) from two centers underwent either MWA ( = 82) or TAE ( = 53) as first-line treatment. We compared the two groups in terms of radiologic response, clinical response, operative time, postoperative analgesic requirements, hospital stay and complications.

RESULTS

MWA had a significantly higher rate of complete radiologic response (89.0% vs. 37.7%, <.001) and complete clinical response (88.6% vs. 69.2%, =.046), fewer minor complications (43.9% vs. 66.0%, =.019), shorter time of using analgesics (<.001) and shorter hospital stays (=.003) than did TAE. The operative time and major complications were comparable between the two groups.

CONCLUSION

Both MWA and TAE are safe and effective in treating patients with large hepatic hemangiomas. MWA had a higher rate of complete response than did TAE, and it was associated with fewer minor complications, faster recovery and shorter hospital stay.

摘要

目的

评估微波消融(MWA)与经导管动脉栓塞术(TAE)治疗大型肝血管瘤的安全性和疗效。

材料与方法

来自两个中心的135例有症状或/和血管瘤增大(5 - 10厘米)的患者接受了MWA(n = 82)或TAE(n = 53)作为一线治疗。我们比较了两组在影像学反应、临床反应、手术时间、术后镇痛需求、住院时间和并发症方面的情况。

结果

与TAE相比,MWA的完全影像学反应率显著更高(89.0%对37.7%,P <.001)和完全临床反应率更高(88.6%对69.2%,P =.046),轻微并发症更少(43.9%对66.0%,P =.019),使用镇痛药时间更短(P <.001)且住院时间更短(P =.003)。两组的手术时间和主要并发症相当。

结论

MWA和TAE在治疗大型肝血管瘤患者方面都是安全有效的。MWA的完全缓解率高于TAE,且并发症少、恢复快、住院时间短。

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