Biophysics Department, Faculty of Science, 63526Cairo University, Giza, Egypt.
Pathology Department, Faculty of Veterinary Medicine, 63526Cairo University, Giza, Egypt.
Hum Exp Toxicol. 2021 Jan;40(1):136-147. doi: 10.1177/0960327120946470. Epub 2020 Aug 7.
In this study, the impact of standard 2.45 GHz radio frequency source (averaged whole-body specific absorption rate 0.01 W kg 24 h daily for 40 consecutive days) on the liver of Wistar female rats was investigated. The rats were randomly divided into control and Wi-Fi-exposed groups. At the end of the exposure, liver samples were dissected from rats. Rats' livers were inspected through the evaluation of some oxidative stress parameters and the evaluation of glutamic oxaloacetic transaminase and glutamic-pyruvic transaminase levels as well as through the molecular investigation using Fourier transform infrared spectroscopy. Histopathological examination in addition to ultrastructure examination was also performed. The present data revealed that Wi-Fi exposure leads to severe oxidative stress in the rat liver. Furthermore, Wi-Fi exposure resulted in deleterious effects in the liver function and alters its molecular structure. Moreover, severe histological and ultrastructural alterations are reported in the hepatic tissues points to hepatotoxic effects induced by Wi-Fi exposure. In conclusion, care must be taken when using Wi-Fi emitting devices due to their severe impact on the liver. Public awareness of the need to decrease exposure time and increase the distance from Wi-Fi exposure sources must be raised wherever possible.
本研究旨在探究标准 2.45GHz 射频源（平均全身比吸收率为 0.01W/kg，每天 24 小时，连续 40 天）对 Wistar 雌性大鼠肝脏的影响。将大鼠随机分为对照组和 Wi-Fi 暴露组。暴露结束后，从大鼠中取出肝脏样本。通过评估一些氧化应激参数以及谷氨酸草酰乙酸转氨酶和谷氨酸丙酮酸转氨酶水平，同时使用傅里叶变换红外光谱进行分子研究，对大鼠的肝脏进行检查。此外，还进行了组织病理学检查和超微结构检查。目前的数据表明，Wi-Fi 暴露会导致大鼠肝脏严重的氧化应激。此外，Wi-Fi 暴露会对肝功能造成有害影响，并改变其分子结构。此外，肝组织中严重的组织学和超微结构改变表明 Wi-Fi 暴露会引起肝毒性作用。总之，由于 Wi-Fi 发射设备对肝脏有严重影响，因此在使用时必须小心。必须提高公众对减少暴露时间和增加与 Wi-Fi 辐射源距离的必要性的认识，尽可能在所有地方提高公众的认识。
