Bruno Kessler Foundation, Trento, Italy.
Directorate General for Health, Lombardy Region, Milan, Italy.
Euro Surveill. 2020 Aug;25(31). doi: 10.2807/1560-7917.ES.2020.25.31.2001383.
We analysed 5,484 close contacts of coronavirus disease (COVID-19) cases in Italy, all tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Infection fatality ratio was 0.43% (95% confidence interval (CI): 0.21-0.79) for individuals younger than 70 years and 10.5% (95% CI: 8.0-13.6) for older individuals. Risk of death after infection was 62% lower (95% CI: 31-80) in clusters identified after 16 March 2020 and 1.8-fold higher for males (95% CI: 1.03-3.16).
我们分析了意大利 5484 名新冠肺炎病例的密切接触者,他们均接受了严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)检测。对于年龄小于 70 岁的个体,感染病死率为 0.43%(95%置信区间:0.21-0.79),对于年龄较大的个体为 10.5%(95%置信区间:8.0-13.6)。2020 年 3 月 16 日之后确定的集群中,感染后的死亡风险降低了 62%(95%置信区间:31-80),男性的风险增加了 1.8 倍(95%置信区间:1.03-3.16)。