Department of Infectious Diseases, West German Centre of Infectious Diseases, Universitätsmedizin Essen, University Duisburg-Essen, Germany.
Department of Infectious Diseases, West German Centre of Infectious Diseases, Universitätsmedizin Essen, University Duisburg-Essen, Germany; Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Am J Infect Control. 2020 Oct;48(10):1273-1275. doi: 10.1016/j.ajic.2020.07.031. Epub 2020 Aug 4.
The coronavirus SARS-CoV-2 pandemic became a global health burden. We determined the susceptibility of SARS-CoV-2 to irradiation with ultraviolet light. The virus was highly susceptible to ultraviolet light. A viral stock with a high infectious titer of 5 × 10 TCID/mL was completely inactivated by UVC irradiation after nine minutes of exposure. The UVC dose required for complete inactivation was 1,048 mJ/cm. UVA exposure demonstrated only a weak effect on virus inactivation over 15 minutes. Hence, inactivation of SARS-CoV-2 by UVC irradiation constitutes a reliable method for disinfection purposes in health care facilities and for preparing SARS-CoV-2 material for research purpose.
新型冠状病毒（SARS-CoV-2）疫情已成为全球健康负担。我们确定了 SARS-CoV-2 对紫外线照射的敏感性。该病毒对紫外线高度敏感。在暴露九分钟后，具有高感染滴度 5×10 TCID/mL 的病毒储备完全被 UVC 照射灭活。完全灭活所需的 UVC 剂量为 1,048 mJ/cm。在 15 分钟内，UVA 照射对病毒灭活仅表现出微弱的作用。因此，UVC 照射灭活 SARS-CoV-2 是医疗机构消毒和为研究目的制备 SARS-CoV-2 材料的可靠方法。
