Department of Hydraulic and Environmental Engineering, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Department of Hydraulic and Environmental Engineering, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Chemosphere. 2021 Jan;262:127840. doi: 10.1016/j.chemosphere.2020.127840. Epub 2020 Aug 3.
This work assessed the effect of the antibiotics trimethoprim (TMP) and sulfamethoxazole (SMX) on the granulation process, microbiology, and organic matter and nutrient removal of an aerobic granular sludge (AGS) system. In addition, after the maturation stage, the impact of the redox mediator anthraquinone-2,6-disulfonate (AQDS) (25 μM) on the biotransformation of the antibiotics was evaluated. The reactor R1 was maintained as a control, and the reactor R2 was supplemented with TMP and SMX (200 μg L). The ability to remove C, N, and P was similar between the reactors. However, the structural integrity of the AGS was impaired by the antibiotics. Low TMP (∼30%) and SMX (∼60%) removals were achieved when compared to anaerobic or floccular biomass aerobic systems. However, when the system was supplemented with AQDS, an increase in the removal of TMP (∼75%) and SMX (∼95%) was observed, possibly due to the catalytic action of the redox mediator on cometabolic processes. Regarding the microbial groups, whereas Proteobacteria and Bacterioidetes increased, Planctomycetes decreased in both reactors. However, TMP and SMX presence seemed to inhibit or favor some genera during the formation of the granules, possibly due to their bactericidal action.
这项工作评估了抗生素甲氧苄啶（TMP）和磺胺甲恶唑（SMX）对好氧颗粒污泥（AGS）系统的颗粒化过程、微生物学、有机物和养分去除的影响。此外，在成熟阶段后，评估了氧化还原介体蒽醌-2,6-二磺酸钠（AQDS）（25 μM）对抗生素生物转化的影响。反应器 R1 作为对照保持不变，而反应器 R2 则补充了 TMP 和 SMX（200 μg L）。两个反应器的 C、N 和 P 去除能力相似。然而，抗生素破坏了 AGS 的结构完整性。与厌氧或絮状生物好氧系统相比，TMP（30%）和 SMX（60%）的去除率较低。然而，当系统中添加 AQDS 时，TMP（75%）和 SMX（95%）的去除率增加，这可能是由于氧化还原介体对共代谢过程的催化作用。关于微生物群，在两个反应器中，变形菌门和拟杆菌门增加，而浮霉菌门减少。然而，TMP 和 SMX 的存在似乎在颗粒形成过程中抑制或有利于某些属，这可能是由于它们的杀菌作用。
