Lee Kyujin, Ko Duk Han, Lee Ji Young
Institution of Sports Science, Seoul National University, Seoul, Republic of Korea.
Department of Sports Science Convergence, Dongguk University, Seoul, Republic of Korea.
Diabetes Metab Syndr Obes. 2020 Jul 10;13:2455-2463. doi: 10.2147/DMSO.S257063. eCollection 2020.
One cause of metabolic syndrome (MetS) is inactivity. This study analyzed the prevalence of MetS due to causes of activity limitation (AL) in adults over 40 years old.
Participants included 2885 people aged 40-79 (1198 men and 1687 women) who completed the Korean National Health and Nutrition Survey (KNHANES) conducted between 2013 and 2017. They were divided into two groups based on age: the middle age group (MA) included 1148 total participants, 515 men and 633 women from 40-59 years old; the older age group (OA) included 1737 total participants, 683 men and 1054 women from 60-79 years old. MetS was diagnosed according to the Third Report of the National Cholesterol Education Program and the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (NCEP-ATP III). Logistic regression was conducted to calculate the odds ratio for MetS prevalence.
The prevalence of MetS in people with AL increased 1.432-fold in the MA men group, 1.511-fold in the OA men group, 1.546-fold in the MA women group, and 1.565-fold in the OA women group. There were several causes of AL; people with physical activity for diabetes mellitus and hypertension increased MetS prevalence in both sexes and all age groups: MA men group (OR=3.216, 95% CI=1.852-7.354, =0.034), MA women group (OR=2.159, 95% CI=1.854-5.346, =0.032), OA men group (OR=3.200, 95% CI=1.235-7.841, =0.009), and OA women group (OR=3.444, 95% CI=1.310-6.627, =0.008). Also, mental problems in the MA men group (OR=2.284, 95% CI=1.591-4.986, =0.012) and OA men group (OR=1.149, 95% CI=1.017-2.941, =0.012), and musculoskeletal problems in the MA women group (OR=1.784, 95% CI=1.102-2.902, =0.021) and OA women group (OR=1.459, 95% CI=1.054-1.993, =0.004) increased the prevalence.
The prevalence of MetS due to activity limitation was increased in MA and OA groups. Activity limitation increased the MetS prevalence from 1.4- to 1.5-times, Therefore, to prevent metabolic syndrome, physical activity should be increased, and guidelines should be presented according to the activity limitation causes, age, and sex.
代谢综合征（MetS）的一个病因是缺乏运动。本研究分析了40岁以上成年人因活动受限（AL）导致的MetS患病率。
参与者包括2885名年龄在40 - 79岁之间的人（1198名男性和1687名女性），他们完成了2013年至2017年期间进行的韩国国家健康与营养调查（KNHANES）。根据年龄将他们分为两组：中年组（MA）共有1148名参与者，其中40 - 59岁的男性515名，女性633名；老年组（OA）共有1737名参与者，其中60 - 79岁的男性为683名，女性为1054名。根据美国国家胆固醇教育计划第三次报告以及成人高血胆固醇检测、评估和治疗专家小组（NCEP - ATP III）的标准诊断MetS。进行逻辑回归以计算MetS患病率的比值比。
AL人群中MetS的患病率在MA男性组中增加了1.432倍，在OA男性组中增加了1.511倍，在MA女性组中增加了1.546倍，在OA女性组中增加了1.565倍。AL有多种原因；患有糖尿病和高血压而进行身体活动的人群在所有性别和年龄组中均增加了MetS患病率：MA男性组（OR = 3.216，95% CI = 1.852 - 7.354，P = 0.034），MA女性组（OR = 2.159，95% CI = 1.854 - 5.346，P = 0.032），OA男性组（OR = 3.200，95% CI = 1.235 - 7.841，P = 0.009），OA女性组（OR = 3.444，95% CI = 1.310 - 6.627，P = 0.008）。此外，MA男性组（OR = 2.284，95% CI = 1.591 - 4.986，P = 0.012）和OA男性组（OR = 1.149，95% CI = 1.017 - 2.941，P = 0.012）的心理问题，以及MA女性组（OR = 1.784，95% CI = 1.102 - 2.902，P = 0.021）和OA女性组（OR = 1.459，95% CI = 1.054 - 1.993，P = 0.004）的肌肉骨骼问题均增加了患病率。
MA组和OA组中因活动受限导致的MetS患病率增加。活动受限使MetS患病率增加了1.4至1.5倍。因此，为预防代谢综合征，应增加身体活动，并根据活动受限原因、年龄和性别制定相应指南。
