Almehmadi Mazen M
Clinical Laboratory, Taif University, Taif, SAU.
Cureus. 2020 Jul 2;12(7):e8962. doi: 10.7759/cureus.8962.
Leukocytosis is common among patients suffering from cancer when leukocytes count exceeds 11,000 cells per mm. This is a usual immune response toward infection and foreign elements. This leads to the release of inflammatory mediators at the targeted site. Studies have found leukocytes count increase in diabetes mellitus patients. Random glucose level indicates the patient is at risk of developing diabetes mellitus. In this study, the association between random glucose level and leukocytes count in female cancer patients is evaluated. About 210 cancer patients included in this study and the results have indicated a positive association between high glucose level and high leukocyte count. This indicates poor prognosis of the patients as high glucose levels increase tumor cell proliferation and high leukocytes count can induce inflammation leading to the progression of cancer and increase mortality rate.
当白细胞计数超过每立方毫米11,000个细胞时，白细胞增多症在癌症患者中很常见。这是对感染和外来物质的一种常见免疫反应。这会导致在靶位点释放炎症介质。研究发现糖尿病患者的白细胞计数会增加。随机血糖水平表明患者有患糖尿病的风险。在这项研究中，评估了女性癌症患者随机血糖水平与白细胞计数之间的关联。本研究纳入了约210名癌症患者，结果表明高血糖水平与高白细胞计数之间存在正相关。这表明患者预后较差，因为高血糖水平会增加肿瘤细胞增殖，而高白细胞计数会诱发炎症，导致癌症进展并增加死亡率。
