Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Handb Clin Neurol. 2020;172:187-199. doi: 10.1016/B978-0-444-64240-0.00011-8.
Migraine prevalence is three times higher in women than in men during fertile years, which is mainly due to sex hormone differences. The majority of women suffering from migraine without aura report improvement of their migraine attacks during pregnancy. Migraine attacks with aura can also improve during pregnancy, but more often remain the same or worsen. Anovulation caused by lactation is generally associated with a decrease in migraine attacks in breastfeeding women. This chapter describes the current knowledge on acute and prophylactic treatment options of migraine and other primary headache disorders during pregnancy and lactation. Further, clinical profiles of secondary headaches during pregnancy and the postpartum period are summarized.
偏头痛在生育期女性中的患病率是男性的三倍，这主要归因于性激素的差异。大多数无先兆偏头痛女性在怀孕期间偏头痛发作会改善。有先兆偏头痛也可能在怀孕期间改善，但更常见的是保持不变或恶化。哺乳期因无排卵导致的偏头痛发作通常会减少。本章描述了目前关于妊娠和哺乳期偏头痛和其他原发性头痛疾病的急性和预防性治疗选择的知识。此外，还总结了妊娠和产后期间继发性头痛的临床特征。
