Departments of Pediatrics.
Neurosurgery.
J Pediatr Hematol Oncol. 2021 May 1;43(4):e505-e507. doi: 10.1097/MPH.0000000000001905.
Growing teratoma syndrome is a well-recognized condition associated with both intracranial and extracranial nongerminomatous germ cell tumors (NGGCTs), which mostly manifest as rapid growth of cystic and solid components during or within several months after treatment. Here, we report a patient with NGGCT who experienced slow growth of intracranial growing teratoma syndrome with intraventricular lipid accumulation over 10 years without any clinical symptoms. Considering the clinicopathologic heterogeneity of this syndrome, long-term clinical and radiologic follow-up is required for all patients with intracranial NGGCT.
种植性畸胎瘤综合征是一种与颅内和颅外非生殖细胞肿瘤(NGGCT)相关的公认疾病,其主要表现为治疗期间或治疗后数月内囊性和实性成分的快速生长。在此,我们报告了一例 NGGCT 患者,其颅内种植性畸胎瘤综合征缓慢生长,10 多年来脑室中有脂质堆积,但无任何临床症状。鉴于该综合征的临床病理异质性,所有颅内 NGGCT 患者均需要进行长期的临床和影像学随访。