From the Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA (Dr. Wustrack), and the Division of Orthopaedic Oncology, Department of Orthopaedic Surgery, The Johns Hopkins Hospital, Baltimore, MD (Dr. Rao and Dr. Morris).
J Am Acad Orthop Surg. 2020 Aug 15;28(16):e716-e728. doi: 10.5435/JAAOS-D-18-00491.
Improvements in cancer treatment have led to prolonged survival and increased rates of cure. An estimated 14 million cancer survivors live in the United States. The cornerstones of cancer treatment, including radiation, chemotherapy, and surgery, give rise to a host of chronic health conditions, some of which affect the musculoskeletal system. As survivorship continues to improve, orthopaedic surgeons across all subspecialties will be tasked with managing these complications of treatment. This article reviews orthopaedic health concerns secondary to cancer treatment that are likely to present to orthopaedic surgeons for evaluation, such as osteoporosis, osteonecrosis, secondary malignancies, radiation-associated fractures, exercise tolerance, and perioperative evaluation.
癌症治疗的进步导致了生存期的延长和治愈率的提高。据估计，美国有 1400 万癌症幸存者。癌症治疗的基石，包括放疗、化疗和手术，会引发一系列慢性健康问题，其中一些会影响到肌肉骨骼系统。随着生存状况的持续改善，所有亚专业的骨科医生都将负责治疗这些并发症。本文回顾了癌症治疗后可能会出现的骨科健康问题，这些问题可能需要骨科医生进行评估，如骨质疏松症、骨坏死、继发性恶性肿瘤、放射性骨折、运动耐量和围手术期评估。
