阻碍因素对 HIV 感染者丙型肝炎病毒转诊倾向的影响。
The role of barriers to care on the propensity for hepatitis C virus nonreferral among people living with HIV.
机构信息
Division of Infectious Diseases and Global Public Health, Department of Medicine.
Skaggs School of Pharmacy and Pharmaceutical Sciences.
出版信息
AIDS. 2020 Sep 1;34(11):1681-1683. doi: 10.1097/QAD.0000000000002610.
Abstract
: Twenty-five percent of HIV/hepatitis C virus (HCV) coinfected patients were not referred for HCV treatment despite unrestricted access in California to direct-acting antivirals (DAA) in 2018. Having unstable housing and ongoing drug use directly affected HCV treatment nonreferral. However, psychiatric history and alcohol use impacted HCV treatment nonreferral through the mediation of not being engaged in HIV care. Achieving HCV elimination requires DAA treatment outside conventional health settings, including substance rehabilitation centers, mental health crisis houses, and homeless shelters.
摘要
2018 年，尽管加利福尼亚州放宽了直接作用抗病毒药物 (DAA) 的使用限制，但仍有 25%的 HIV/丙型肝炎病毒 (HCV) 合并感染患者未被转介接受 HCV 治疗。无稳定住所和持续吸毒直接影响 HCV 治疗的转介。然而，精神病史和酒精使用通过影响 HIV 护理的参与度，间接影响 HCV 治疗的转介。要实现 HCV 的消除，需要在常规卫生保健环境之外使用 DAA 进行治疗，包括物质康复中心、精神健康危机收容所以及收容所。
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