Frishman W H, Teicher M
Albert Einstein College of Medicine, Bronx, New York.
Med Clin North Am. 1988 Jan;72(1):185-96. doi: 10.1016/s0025-7125(16)30789-1.
Many of the available nitrate preparations, beta-adrenergic blockers, and calcium antagonists appear to be useful in patients with painful and silent ischemic episodes detected on the ECG (Table 1). More controlled studies need to be done using standardized methodologies for assessing silent myocardial ischemia, to evaluate and compare the different antianginal medications. It is fortunate, however, that the nitrates, beta-blockers, and calcium antagonists, used alone and in combination, appear to have favorable effects not only on painful ischemic episodes but also on those ischemic episodes not associated with pain.
许多现有的硝酸盐制剂、β肾上腺素能阻滞剂和钙拮抗剂似乎对心电图检测出有疼痛性和无症状性缺血发作的患者有用（表1）。需要使用标准化方法进行更多对照研究，以评估无症状性心肌缺血，从而评估和比较不同的抗心绞痛药物。然而，幸运的是，硝酸盐、β受体阻滞剂和钙拮抗剂单独使用或联合使用，似乎不仅对疼痛性缺血发作有良好效果，而且对那些与疼痛无关的缺血发作也有良好效果。
