National Office for Maternal and Child Health Surveillance of China, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Ren Min South Road Section 3 No. 17, Chengdu, Sichuan, China.
Sci Rep. 2020 Aug 7;10(1):13328. doi: 10.1038/s41598-020-70257-x.
To determine whether the nationwide program 'Reducing maternal mortality and eliminating neonatal tetanus' contributed to the rapid decline in China's maternal mortality ratio (MMR) and neonatal tetanus elimination by enhancing hospital delivery, we compared MMR and neonatal tetanus incidence rate (NTR) reductions by province from 2000 to 2013. The difference-in-difference method was used to analyze the program effect. Long-term effects were analyzed relative to MMR and NTR in 2000 and 2002, respectively, while short-term effects in a given year were analyzed relative to MMR and NTR in the preceding year. The national program was associated with a faster decline in MMR in the long term. The rate of decline showed an inverse 'U' shape from 2000 to 2013, peaking in 2009. The program had a short-term effect in MMR reduction in 2005, 2007, and 2009. The program was also associated with faster decline in NTR in the short term at some time points, but this association was not consistent and was not found in the long term. In conclusion, the program accelerated decline of MMR from 2000 to 2013 but did not clearly reduce NTR at the province level. Therefore, this targeted program worked efficiently in resource-poor areas.
为了确定全国范围内的“降低孕产妇死亡率和消除新生儿破伤风”项目是否通过促进医院分娩来促进中国孕产妇死亡率(MMR)和新生儿破伤风消除的快速下降,我们比较了 2000 年至 2013 年各省 MMR 和新生儿破伤风发病率(NTR)的下降情况。采用差异法分析项目效果。长期效果分别相对于 2000 年和 2002 年的 MMR 和 NTR 进行分析,而当年的短期效果相对于前一年的 MMR 和 NTR 进行分析。国家项目与 MMR 的长期下降速度较快有关。从 2000 年到 2013 年,下降率呈反“U”形,在 2009 年达到峰值。该项目在 2005 年、2007 年和 2009 年的 MMR 降低方面具有短期效果。该项目在某些时间点还与 NTR 的短期快速下降有关,但这种关联并不一致,也没有在长期内发现。总之,该项目加速了 2000 年至 2013 年 MMR 的下降速度,但在省级层面上并没有明显降低 NTR。因此,该有针对性的项目在资源匮乏地区的效果显著。