Akiyama H, Krigel R L
Department of Medicine, Fox Chase Cancer Center, Philadelphia, PA 19111.
Am J Hematol. 1988 Feb;27(2):115-7. doi: 10.1002/ajh.2830270209.
Extramedullary plasmacytomas are unusual plasma cell tumors arising outside the bone marrow. Most extramedullary plasmacytomas are solitary, but occasionally they disseminate, usually in conjunction with systemic myelomatosis. The authors report a case of disseminated extramedullary plasmacytoma with a picture suggestive of metastatic pancreatic carcinoma. This unusual presentation reconfirms the need for tissue diagnosis in all suspected cases of pancreatic carcinoma and demonstrates that extramedullary plasmacytoma can be an aggressive cancer without any sign of osseous or systemic disease.
髓外浆细胞瘤是发生于骨髓外的罕见浆细胞肿瘤。大多数髓外浆细胞瘤是孤立性的,但偶尔也会播散,通常与系统性骨髓瘤相关。作者报告了一例播散性髓外浆细胞瘤,其表现提示转移性胰腺癌。这种不寻常的表现再次证实了所有疑似胰腺癌病例都需要进行组织诊断,并表明髓外浆细胞瘤可以是一种侵袭性癌症,而没有任何骨或全身性疾病的迹象。